ArticleScientific reports2018
Chronic exposure to low dose of bisphenol A impacts on the first round of spermatogenesis via SIRT1 modulation.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
27 citing papers in PubMed, 80 citations in OpenAlex.
- Article
- PFOS caused fertility defects and disrupted spermatogenic gene networks in medaka with a transgenerational history of ancestral BPA exposure.Environmental research · 2025Article
- Review
- Variation of sperm quality and circular RNA content in men exposed to environmental contamination with heavy metals in 'Land of Fires', Italy.Human reproduction (Oxford, England) · 2024Article
- The Bacterial GJournal of chemical ecology · 2023Article
- Re-evaluation of the risks to public health related to the presence of bisphenol A (BPA) in foodstuffs.EFSA journal. European Food Safety Authority · 2023Article
- Fetal Exposure to Endocrine Disrupting-Bisphenol A (BPA) Alters Testicular Fatty Acid Metabolism in the Adult Offspring: Relevance to Sperm Maturation and Quality.International journal of molecular sciences · 2023Article
- Article
- The interplay between kisspeptin and endocannabinoid systems modulates male hypothalamic and gonadic control of reproductionFrontiers in endocrinology · 2023Article
- Impact of bisphenol-A on the spliceosome and meiosis of sperm in the testis of adolescent mice.BMC veterinary research · 2022Article
- SIRT1: A Key Player in Male Reproduction.Life (Basel, Switzerland) · 2022Review
- Multi-Systemic Alterations by Chronic Exposure to a Low Dose of Bisphenol A in Drinking Water: Effects on Inflammation and NADInternational journal of molecular sciences · 2021Article
- The possible role of sirtuins in male reproduction.Molecular and cellular biochemistry · 2021Review
- Bisphenol F Exposure in Adolescent Heterogeneous Stock Rats Affects Growth and Adiposity.Toxicological sciences : an official journal of the Society of Toxicology · 2021Article
- SIRT1 Expression and Regulation in the Primate Testis.International journal of molecular sciences · 2021Article
- Microplastics: A Threat for Male Fertility.International journal of environmental research and public health · 2021Review
- Sirt1 Activity in the Brain: Simultaneous Effects on Energy Homeostasis and Reproduction.International journal of environmental research and public health · 2021Review
- The Complex Interplay between Endocannabinoid System and the Estrogen System in Central Nervous System and Periphery.International journal of molecular sciences · 2021Review
- Mitochondrial Reactive Oxygen Species (ROS) Production Alters Sperm Quality.Antioxidants (Basel, Switzerland) · 2021Review
- Low Doses of Glyphosate/Roundup Alter Blood-Testis Barrier Integrity in Juvenile Rats.Frontiers in endocrinology · 2021Article
Corrections and comments
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Authors and funding
15 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Spermatogenesis depends on endocrine, autocrine and paracrine communications along the hypothalamus-pituitary-gonad axis. Bisphenol A (BPA), an estrogen-mimic endocrine disrupting chemical, is an environmental contaminant used to manufacture polycarbonate plastics and epoxy resins with toxic effects for male reproduction. Here we investigated whether the chronic exposure to low BPA doses affects spermatogenesis through the modulation of SIRT1, a NAD
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.