Evidence map›Paper›PMID 29440558›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and Phosphatase Regulation of Ca

Jennifer L Sanderson, John D Scott, Mark L Dell'Acqua

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 75 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Ketamine Reverses Chronic Stress-Induced Behavioral Changes via the Expression of CaFASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2025
    Article
  8. Signaling by intracellular βCell reports · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Diverging from the Norm: Reevaluating What Miniature Excitatory Postsynaptic Currents Tell Us about Homeostatic Synaptic Plasticity.The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry · 2024
    Review
  15. Article
  16. Article
  17. Review
  18. Loss of Depalmitoylation Disrupts Homeostatic Plasticity of AMPARs in a Mouse Model of Infantile Neuronal Ceroid Lipofuscinosis.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 3 countries.

Jennifer L SandersonDepartment of Pharmacology.
John D ScottHoward Hughes Medical Institute, and.ORCID 0000-0002-0367-8146
Mark L Dell'AcquaDepartment of Pharmacology, mark.dellacqua@ucdenver.edu.ORCID 0000-0003-3798-3461
Howard Hughes Medical Institute · USInstitute of Pharmacology · CZUniversidad Centroamericana de Ciencias Sociales · CR

Funding

Regulation of Calcium-permeable AMPA Receptors by AKAP79 Postsynaptic SignalingR01NS040701 · NINDS · UNIVERSITY OF COLORADO DENVER · PI DELL'ACQUA, MARK L · 2001 to 2023
$7.7M
NINDS NIH HHS R01 NS040701
6 · The paper itself

Abstract

Neuronal information processing requires multiple forms of synaptic plasticity mediated by NMDARs and AMPA-type glutamate receptors (AMPARs). These plasticity mechanisms include long-term potentiation (LTP) and long-term depression (LTD), which are Hebbian, homosynaptic mechanisms locally regulating synaptic strength of specific inputs, and homeostatic synaptic scaling, which is a heterosynaptic mechanism globally regulating synaptic strength across all inputs. In many cases, LTP and homeostatic scaling regulate AMPAR subunit composition to increase synaptic strength via incorporation of Ca

Indexed as

Action PotentialsA Kinase Anchor ProteinsAnimalsElectrophysiological PhenomenaExcitatory Postsynaptic PotentialsFemaleGene Knock-In TechniquesHomeostasisLong-Term PotentiationMaleMiceNeuronal PlasticityPhosphoric Monoester HydrolasesPrimary Cell CultureReceptors, AMPAReceptors, N-Methyl-D-AspartateA Kinase Anchor Proteinscalcineurin phosphatasePhosphoric Monoester HydrolasesReceptors, AMPAReceptors, N-Methyl-D-AspartateAKAP150Ca2+-permeable AMPA receptorcalcineurinhomeostatic plasticityLTPPKA

Identifiers

PMID29440558
PMCPMC5852664
OpenAlexW2787193915

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.