ArticleProceedings of the National Academy of Sciences of the United States of America2018
GABAergic inhibition of leg motoneurons is required for normal walking behavior in freely moving
Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
20 citing papers in PubMed, 47 citations in OpenAlex.
- Nigral stimulation for freezing of gait: kinematic gait parameters inform optimization of stimulation frequency.Journal of neuroengineering and rehabilitation · 2025Trial
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- Two classes of amine/glutamate multi-transmitter neurons innervate Drosophila internal male reproductive organs.bioRxiv : the preprint server for biology · 2025Article
- GABAergic neuronal dysfunction underlies tremor in spinocerebellar ataxia 3.Disease models & mechanisms · 2025Article
- Divergent neural circuits for proprioceptive and exteroceptive sensing of the Drosophila leg.Nature communications · 2025Article
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- Synaptic architecture of leg and wing premotor control networks inbioRxiv : the preprint server for biology · 2024Article
- G3'MTMD3 in the insect GABA receptor subunit, RDL, confers resistance to broflanilide and fluralaner.PLoS genetics · 2023Article
- Ammonium transporter AcAmt mutagenesis uncovers reproductive and physiological defects without impacting olfactory responses to ammonia in the malaria vector mosquito Anopheles coluzzii.Insect biochemistry and molecular biology · 2021Article
- Regulation of coordinated muscular relaxation in Drosophila larvae by a pattern-regulating intersegmental circuit.Nature communications · 2021Article
- Navigation of a Freely Walking Fruit Fly in Infinite Space Using a Transparent Omnidirectional Locomotion Compensator (TOLC).Sensors (Basel, Switzerland) · 2021Article
- A size principle for recruitment ofeLife · 2020Article
- A single-cell transcriptomic atlas of the adulteLife · 2020Article
- A locomotor assay reveals deficits in heterozygous Parkinson's disease model and proprioceptive mutants in adultProceedings of the National Academy of Sciences of the United States of America · 2019Article
- Fully automated leg tracking of Drosophila neurodegeneration models reveals distinct conserved movement signatures.PLoS biology · 2019Article
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- Understanding the Consequences of Repetitive Subconcussive Head Impacts in Sport: Brain Changes and Dampened Motor Control Are Seen After Boxing Practice.Frontiers in human neuroscience · 2019Article
- Article
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Walking is a complex rhythmic locomotor behavior generated by sequential and periodical contraction of muscles essential for coordinated control of movements of legs and leg joints. Studies of walking in vertebrates and invertebrates have revealed that premotor neural circuitry generates a basic rhythmic pattern that is sculpted by sensory feedback and ultimately controls the amplitude and phase of the motor output to leg muscles. However, the identity and functional roles of the premotor interneurons that directly control leg motoneuron activity are poorly understood. Here we take advantage of the powerful genetic methodology available in
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.