Evidence map›Paper›PMID 29440366›Full record

ArticleInfection and immunity2018

Salmonella enterica Serovar Typhimurium Increases Functional PD-L1 Synergistically with Gamma Interferon in Intestinal Epithelial Cells via Salmonella Pathogenicity Island 2.

J M Sahler, C R Eade, C Altier, J C March

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Overcoming resistance to anti-PD-1/PD-L1 therapy in cancer.Cancer drug resistance (Alhambra, Calif.) · 2026
    Review
  4. Review
  5. The renaissance ofFrontiers in immunology · 2026
    Review
  6. Review
  7. Exploiting bacteria for cancer immunotherapy.Nature reviews. Clinical oncology · 2024
    Review
  8. Article
  9. Article
  10. Perspectives on OncolyticFrontiers in immunology · 2021
    Review
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

J M SahlerBiological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA.
C R EadePopulation Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.ORCID https://orcid.org/0000-0002-1009-0420
C AltierPopulation Medicine and Diagnostic Sciences, College of Veterinary Medicine, Cornell University, Ithaca, New York, USA.
J C MarchBiological and Environmental Engineering, College of Agriculture and Life Sciences, Cornell University, Ithaca, New York, USA jcm224@cornell.edu.
Cornell University · US

Funding

Engineering commensal bacteria as therapeutic signal mediatorsDP2OD007155 · OD · CORNELL UNIVERSITY · PI MARCH, JOHN C · 2010 to 2015
$2.9M
NIH HHS DP2 OD007155
6 · The paper itself

Abstract

Nontyphoidal serovars of

Indexed as

Epithelial CellsHumansInterferon-gammaIntestinesProgrammed Cell Death 1 ReceptorSalmonella entericaInterferon-gammaProgrammed Cell Death 1 ReceptorPD-L1Salmonella

Identifiers

PMID29440366
PMCPMC5913837
OpenAlexW2786686327

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.