Evidence map›Paper›PMID 29440310›Full record

ArticleMolecular and cellular biology2018

Asp1 Bifunctional Activity Modulates Spindle Function via Controlling Cellular Inositol Pyrophosphate Levels in Schizosaccharomyces pombe.

Marina Pascual-Ortiz, Adolfo Saiardi, Eva Walla, Visnja Jakopec, Natascha A Künzel, Ingrid Span, Anand Vangala, Ursula Fleig

Abstract read
In one paragraph

Article in Molecular and cellular biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed
7.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 55 citations in OpenAlex.

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  13. An In Vivo Yeast-Based Activity Assay for the PPIP5K Family.Methods in molecular biology (Clifton, N.J.) · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Marina Pascual-OrtizEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany.
Adolfo SaiardiMedical Research Council Laboratory for Molecular Cell Biology, University College London, London, United Kingdom.
Eva WallaEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany.
Visnja JakopecEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany.
Natascha A KünzelEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany.
Ingrid SpanInstitut für Physikalische Biologie, Heinrich Heine Universität, Düsseldorf, Germany.
Anand VangalaEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany.
Ursula FleigEukaryotische Mikrobiologie, Institut für Funktionelle Genomforschung der Mikroorganismen, Heinrich Heine Universität, Düsseldorf, Germany fleigu@hhu.de.
Heinrich Heine University Düsseldorf · DEMRC Laboratory for Molecular Cell Biology · GB

Funding

Medical Research Council MC_U122680443Medical Research Council MC_UU_00012/4Medical Research Council MC_UU_12018/4
6 · The paper itself

Abstract

The generation of two daughter cells with the same genetic information requires error-free chromosome segregation during mitosis. Chromosome transmission fidelity is dependent on spindle structure/function, which requires Asp1 in the fission yeast

Indexed as

Chromosome SegregationCytoskeletal ProteinsInositolInositol PhosphatesKinesinsMicrotubule-Associated ProteinsMicrotubulesMitosisMultifunctional EnzymesPhosphotransferases (Phosphate Group Acceptor)PyrophosphatasesSchizosaccharomycesSchizosaccharomyces pombe ProteinsSpindle ApparatusSulfite Reductase (NADPH)Asp1 protein, S pombeCut7 protein, S pombeCytoskeletal Proteinsdiphosphoinositol pentakisphosphate kinaseInositolInositol PhosphatesKinesinsMicrotubule-Associated ProteinsMultifunctional EnzymesPhosphotransferases (Phosphate Group Acceptor)PyrophosphatasesSchizosaccharomyces pombe ProteinsSulfite Reductase (NADPH)chromosome segregationinositol pyrophosphatemicrotubulemitosisphosphatasePPIP5K familySchizosaccharomyces pombesignaling moleculesyeast

Identifiers

PMID29440310
PMCPMC5902593
OpenAlexW2803827659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.