Evidence map›Paper›PMID 29440252›Full record

ArticleJournal of bacteriology2018

A Single Amino Acid Change in the Response Regulator PhoP, Acquired during Yersinia pestis Evolution, Affects PhoP Target Gene Transcription and Polymyxin B Susceptibility.

Hana S Fukuto, Viveka Vadyvaloo, Joseph B McPhee, Hendrik N Poinar, Edward C Holmes, James B Bliska

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Journal of bacteriology · 2026
    Article
  2. Review
  3. Article
  4. Lipopolysaccharide of theBiomolecules · 2021
    Review
  5. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  6. ACS infectious diseases · 2021
    Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Co-infection Assay to Determine Yersinia pestis Competitive Fitness in Fleas.Methods in molecular biology (Clifton, N.J.) · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 3 countries.

Hana S FukutoCenter for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA hana.fukuto@stonybrook.edu james.bliska@stonybrook.edu.
Viveka VadyvalooPaul G. Allen School for Global Animal Health, Washington State University, Pullman, Washington, USA.
Joseph B McPheeDepartment of Chemistry and Biology, Ryerson University, Toronto, Canada.
Hendrik N PoinarMcMaster Ancient DNA Center, Department of Anthropology, McMaster University, Hamilton, Canada.
Edward C HolmesMarie Bashir Institute for Infectious Diseases and Biosecurity, The University of Sydney, Sydney, Australia.ORCID https://orcid.org/0000-0001-9596-3552
James B BliskaCenter for Infectious Diseases, Stony Brook University, Stony Brook, New York, USA hana.fukuto@stonybrook.edu james.bliska@stonybrook.edu.ORCID https://orcid.org/0000-0002-6047-8837
Stony Brook University · USCanadian Institute for Advanced Research · CAThe University of Sydney · AUToronto Metropolitan University · CAWashington State University · US

Funding

Regulation of host innate and adaptive immunity by bacterial type III effectorsR01AI099222 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI BLISKA, JAMES B · 2012 to 2025
$5.9M
MOLECULAR MECHANISMS OF YERSINIA PESTIS PERSISTENCE IN THE FLEA VECTORR21AI097974 · NIAID · WASHINGTON STATE UNIVERSITY · PI VADYVALOO, VIVEKA · 2012 to 2013
$377k
NIAID NIH HHS R01 AI099222NIAID NIH HHS R21 AI097974
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Amino Acid SubstitutionAnimalsAnti-Bacterial AgentsBacterial ProteinsEvolution, MolecularGlycineMacrophagesMiceMutationPolymyxin BSerineSiphonapteraTranscription, GeneticVirulenceYersinia pestisAnti-Bacterial AgentsBacterial ProteinsGlycinePhoP protein, BacteriaPolymyxin BSerineevolutionPhoPtranscriptionYersinia pestis

Identifiers

PMID29440252
PMCPMC5892123
OpenAlexW2791126850

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.