Evidence map›Paper›PMID 29440223›Full record

ArticleGenes & development2018

Enhancer transcription: what, where, when, and why?

Nathaniel D Tippens, Anniina Vihervaara, John T Lis

Open access · diamondAbstract readComment
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 104 citations in OpenAlex.

  1. Review
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  5. Potential ofFrontiers in immunology · 2026
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  20. The GRN concept as a guide for evolutionary developmental biology.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023
    Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Nathaniel D TippensDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.
Anniina VihervaaraDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.
John T LisDepartment of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA.
Tri-Institutional PhD Program in Chemical Biology · USCornell University · US

Funding

High-throughput functional characterization of human enhancersUM1HG009393 · NHGRI · CORNELL UNIVERSITY · PI LIS, JOHN T, YU, HAIYUAN · 2017 to 2021
$4.1M
Research and Career Training in Vertebrate Developmental GenomicsT32HD057854 · NICHD · CORNELL UNIVERSITY · PI SCHIMENTI, JOHN C · 2010 to 2020
$1.3M
NHGRI NIH HHS UM1 HG009393NICHD NIH HHS T32 HD057854
6 · The paper itself

Abstract

Following the discovery of widespread enhancer transcription, enhancers and promoters have been found to be far more similar than previously thought. In this issue of

Indexed as

Enhancer Elements, GeneticAnimalsDrosophilaPromoter Regions, Geneticembryonic developmentenhancerseRNApromotersP-TEFbsuperenhancersterminationtranscription

Identifiers

PMID29440223
PMCPMC5828389
OpenAlexW2786732053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.