Evidence map›Paper›PMID 29440198›Full record

ReviewCirculation2018

Developing a Clinical Approach to Air Pollution and Cardiovascular Health.

Michael B Hadley, Jill Baumgartner, Rajesh Vedanthan

Abstract readReview
In one paragraph

Review in Circulation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 65 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
65citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

65 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Quantifying the Health Benefits Linked to Reduced Traffic-Related PMEnvironment & health (Washington, D.C.) · 2026
    Article
  6. Association Between the Use of Solid Fuels in Households and Hypertension in Peru: A Population-Based Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
  7. Article
  8. Review
  9. Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article

5 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Michael B HadleyDepartment of Medicine, Icahn School of Medicine at Mount Sinai, New York (M.B.H.) michael.hadley@mountsinai.org.
Jill BaumgartnerInstitute for Health and Social Policy and Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Quebec, Montreal, Canada (J.B.).
Rajesh VedanthanInstitute for Health and Social Policy and Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Quebec, Montreal, Canada (J.B.).

Funding

Nurse Management of Hypertension in Rural Western KenyaK01TW009218 · FIC · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI VEDANTHAN, RAJESH · 2011 to 2015
$638k
SPatial Analysis of Cardiovascular Events (SPACE) in the Golestan Cohort StudyR21HL140474 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI VEDANTHAN, RAJESH · 2017 to 2018
$254k
CIHR 141959FIC NIH HHS K01 TW009218NHLBI NIH HHS R21 HL140474
6 · The paper itself

Abstract

Nearly 3 billion people are exposed to household air pollution emitted from inefficient cooking and heating stoves, and almost the entire global population is exposed to detectable levels of outdoor air pollution from traffic, industry, and other sources. Over 3 million people die annually of ischemic heart disease or stroke attributed to air pollution, more than from traditional cardiac risk factors such as obesity, diabetes mellitus, or smoking. Clinicians have a role to play in reducing the burden of pollution-attributable cardiovascular disease. However, there currently exists no clear clinical approach to this problem. Here, we provide a blueprint for an evidence-based clinical approach to assessing and mitigating cardiovascular risk from exposure to air pollution. We begin with a discussion of the global burden of pollution-attributable cardiovascular disease, including a review of the mechanisms by which particulate matter air pollution leads to cardiovascular outcomes. Next, we offer a simple patient-screening tool using known risk factors for pollution exposure. We then discuss approaches to quantifying air pollution exposures and cardiovascular risk, including the development of risk maps for clinical catchment areas. We review a collection of interventions for household and outdoor air pollution, which clinicians can tailor to patients and populations at risk. Finally, we identify future research needed to quantify pollution exposures and validate clinical interventions. Overall, we demonstrate that clinicians can be empowered to mitigate the global burden of cardiovascular disease attributable to air pollution.

Indexed as

Evidence-Based PracticeAir PollutionCardiovascular DiseasesEnvironmental ExposureHumansRisk Factorsair pollutioncardiovascular diseasesenvironmental healthglobal healthmyocardial ischemiaparticulate matterstroke

Identifiers

PMID29440198
PMCPMC5950725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.