Evidence map›Paper›PMID 29440162›Full record

ArticleBMJ open2018

Sequelae of multidrug-resistant tuberculosis: protocol for a systematic review and meta-analysis.

Kefyalew Addis Alene, Archie C A Clements, Emma S McBryde, Ernesto Jaramillo, Knut Lonnroth, Debebe Shaweno, Kerri Viney

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. The fight to end tuberculosis: a global challenge in strong partnership.Journal of preventive medicine and hygiene · 2020
    Article
  5. Curdlan LimitsFrontiers in microbiology · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kefyalew Addis AleneResearch School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.
Archie C A ClementsResearch School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.
Emma S McBrydeAustralian Institute of Tropical Health and Medicine, James Cook University, Townsville, Queensland, Australia.
Ernesto JaramilloGlobal TB Programme, World Health Organization, Geneva, Switzerland.
Knut LonnrothDepartment of Public Health Sciences, Karolinska Institutet, Stockholm, Sweden.
Debebe ShawenoDepartment of Medicine, University of Melbourne, Melbourne, Victoria, Australia.
Kerri VineyResearch School of Population Health, College of Health and Medicine, Australian National University, Canberra, Australia.

Funding

World Health Organization 001
6 · The paper itself

Abstract

introductionThe sequelae of multidrug-resistant tuberculosis (MDR-TB) are poorly understood and inconsistently reported. We will aim to assess the existing evidence for the clinical, psychological, social and economic sequelae of MDR-TB and to assess the health-related quality of life in patients with MDR-TB. METHODS AND ANALYSIS: We will perform a systematic review and meta-analysis of published studies reporting sequelae of MDR-TB. We will search PubMed, SCOPUS, ProQuest, Web of Science and PsychINFO databases up to 5 September 2017. MDR-TB sequelae will include any clinical, psychological, social and economic effects as well as health-related quality of life that occur after MDR-TB treatment or illness. Two researchers will screen the titles and abstracts of all citations identified in our search, extract data, and assess the scientific quality using standardised formats. Providing there is appropriate comparability in the studies, we will use a random-effects meta-analysis model to produce pooled estimates of MDR-TB sequelae from the included studies. We will stratify the analyses based on treatment regimen, comorbidities (such as HIV status and diabetes mellitus), previous TB treatment history and study setting. ETHICS AND DISSEMINATION: As this study will be based on published data, ethical approval is not required. The final report will be disseminated through publication in a peer-reviewed scientific journal and will also be presented at relevant conferences. PROSPERO REGISTRATION NUMBER: CRD42017073182.

Indexed as

Quality of LifeAntitubercular AgentsComorbidityHumansMeta-Analysis as TopicResearch DesignSystematic Reviews as TopicTuberculosis, Multidrug-ResistantAntitubercular AgentsMDR-TBmeta-analysismultidrug-resistant tuberculosisprotocolsequelaesystematic review

Identifiers

PMID29440162
PMCPMC5829942

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.