Evidence map›Paper›PMID 29439548›Full record

ArticleInternational journal of molecular sciences2018

Detection of HPV16 in Esophageal Cancer in a High-Incidence Region of Malawi.

Anja Lidwina Geßner, Angelika Borkowetz, Michael Baier, Angela Göhlert, Torsten J Wilhelm, Alexander Thumbs, Eric Borgstein, Lars Jansen, Katrin Beer, Henning Mothes and 1 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 3 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 3 syntheses or guidelines pooled it, 19 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Review
  5. Article
  6. Prevalence of human papillomavirus andInfectious agents and cancer · 2019
    Article
  7. Human Polyomaviruses and Papillomaviruses.International journal of molecular sciences · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Anja Lidwina GeßnerDepartment of General, Visceral and Vascular Surgery, Jena University Hospital-Friedrich-Schiller-University; 07747 Jena, Germany. anja.l.gessner@gmail.com.
Angelika BorkowetzDepartment of Urology, Technische Universität Dresden; 01307 Dresden, Germany. angelika@borkowetz.de.
Michael BaierInstitute for Medical Microbiology, Jena University Hospital-Friedrich-Schiller-University, 07747 Jena, Germany. Michael.Baier@med.uni-jena.de.
Angela GöhlertInstitute for Pathology, Jena University Hospital-Friedrich-Schiller-University, 07743 Jena, Germany. pathologiejena@gmail.com.
Torsten J WilhelmDepartment of Surgery, University Medical Centre Mannheim, 68167 Mannheim, Germany. tjwilhelm@web.de.
Alexander ThumbsDepartment of Surgery, Queen Elizabeth Central Hospital-College of Medicine, Blantyre 3, Malawi. alex_thumbs@hotmail.com.
Eric BorgsteinDepartment of Surgery, Queen Elizabeth Central Hospital-College of Medicine, Blantyre 3, Malawi. eborg@me.com.
Lars JansenDepartment of Gynecology, Jena University Hospital-Friedrich-Schiller-University, 07747 Jena, Germany. Lars.Jansen@med.uni-jena.de.
Katrin BeerDepartment of Gynecology, Jena University Hospital-Friedrich-Schiller-University, 07747 Jena, Germany. Katrin.Beer@med.uni-jena.de.
Henning MothesDepartment of General, Visceral and Vascular Surgery, Jena University Hospital-Friedrich-Schiller-University; 07747 Jena, Germany. Henning.Mothes@med.uni-jena.de.
Matthias DürstDepartment of Gynecology, Jena University Hospital-Friedrich-Schiller-University, 07747 Jena, Germany. matthias.duerst@med.uni-jena.de.ORCID 0000-0003-1235-1150
Jena University Hospital · DEQueen Elizabeth Central Hospital · MWTechnische Universität Dresden · DEUniversity Medical Centre Mannheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study was designed to explore the role of human papillomavirus (HPV) in esophageal squamous cell carcinoma (ESCC). Fifty-five patients receiving diagnostic upper gastrointestinal endoscopy at Zomba Central Hospital or Queen Elizabeth Hospital in Blantyre (Malawi) in 2010, were included in our study. Formalin-fixed paraffin-embedded biopsies were collected for histopathological diagnosis. HPV DNA was detected using multiplex Quantitative PCR (qPCR) and in situ hybridization (ISH). p16

Indexed as

AdultAgedCarcinoma, Squamous CellEsophageal NeoplasmsFemaleHuman papillomavirus 16HumansMalawiMaleMiddle AgedPapillomavirus Infectionsalcoholesophageal squamous cell carcinomahuman Papillomavirusin situ hybridizationKi-67 proliferation indexp16INK4a immunohistochemistrypolymerase chain reactionsmoking

Identifiers

PMID29439548
PMCPMC5855779
OpenAlexW2790800773

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.