Evidence map›Paper›PMID 29439410›Full record

ArticleInternational journal of molecular sciences2018

Potential Antitumor Activity of 2-O-α-d-Glucopyranosyl-6-O-(2-Pentylheptanoyl)-l-Ascorbic Acid.

Kaori Miura, Misaki Haraguchi, Hideyuki Ito, Akihiro Tai

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Antiallergic Activity of 6-Deoxy-2-Molecules (Basel, Switzerland) · 2021
    Article
  5. Review
  6. Therapeutic Perspective of Vitamin C and Its Derivatives.Antioxidants (Basel, Switzerland) · 2019
    Review
  7. Ascorbic Acid in Colon Cancer: From the Basic to the Clinical Applications.International journal of molecular sciences · 2018
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kaori MiuraFaculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 5562 Nanatsuka-cho, Shobara, Hiroshima 727-0023, Japan. q531005dd@ed.pu-hiroshima.ac.jp.
Misaki HaraguchiFaculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 5562 Nanatsuka-cho, Shobara, Hiroshima 727-0023, Japan. q405088xe@ed.pu-hiroshima.ac.jp.
Hideyuki ItoFaculty of Health and Welfare Science, Okayama Prefectural University, 111 Kuboki, Soja, Okayama 719-1197, Japan. hito@fhw.oka-pu.ac.jp.
Akihiro TaiFaculty of Life and Environmental Sciences, Prefectural University of Hiroshima, 5562 Nanatsuka-cho, Shobara, Hiroshima 727-0023, Japan. atai@pu-hiroshima.ac.jp.
Prefectural University of Hiroshima · JPOkayama Prefectural University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravenous administration of high-dose ascorbic acid (AA) has been reported as a treatment for cancer patients. However, cancer patients with renal failure cannot receive this therapy because high-dose AA infusion can have side effects. To solve this problem, we evaluated the antitumor activity of a lipophilic stable AA derivative, 2-

Indexed as

AnimalsAntineoplastic AgentsAscorbic AcidCell Line, TumorFemaleGlucosidesMiceMice, Inbred BALB CNeoplasms, ExperimentalTissue DistributionAntineoplastic AgentsAscorbic AcidGlucosidesacyl ascorbic acidantitumor activityascorbic acidstable ascorbic acid derivatives

Identifiers

PMID29439410
PMCPMC5855757
OpenAlexW2793186108

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.