Evidence map›Paper›PMID 29439409›Full record

ReviewMolecules (Basel, Switzerland)2018

Cancer Targeting and Drug Delivery Using Carbon-Based Quantum Dots and Nanotubes.

Joel Pardo, Zhili Peng, Roger M Leblanc

Abstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

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  16. Curcumin coating: a novel solution to mitigate inherent carbon nanotube toxicity.Journal of materials science. Materials in medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Joel PardoDepartment of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA. jxp1142@miami.edu.
Zhili PengDepartment of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA. z.peng@umiami.edu.ORCID 0000-0001-9688-7504
Roger M LeblancDepartment of Chemistry, University of Miami, 1301 Memorial Drive, Coral Gables, FL 33146, USA. rml@miami.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Currently cancer treatment is in large part non-specific with respect to treatment. Medication is often harsh on patients, whereby they suffer several undesired side effects as a result. Carbon-based nanoparticles have attracted attention in recent years due to their ability to act as a platform for the attachment of several drugs and/or ligands. Relatively simple models are often used in cancer research, wherein carbon nanoparticles are conjugated to a ligand that is specific to an overexpressed receptor for imaging and drug delivery in cancer treatment. These carbon nanoparticles confer unique properties to the imaging or delivery vehicle due to their nontoxic nature and their high fluorescence qualities. Chief among the ongoing research within carbon-based nanoparticles emerge carbon dots (C-dots) and carbon nanotubes (CNTs). In this review, the aforementioned carbon nanoparticles will be discussed in their use within doxorubicin and gemcitabine based drug delivery vehicles, as well as the ligand-mediated receptor specific targeted therapy. Further directions of research in current field are also discussed.

Indexed as

Antineoplastic AgentsDeoxycytidineDoxorubicinDrug CarriersDrug LiberationFluorescent DyesFolic AcidGemcitabineHumansHyaluronic AcidMolecular Targeted TherapyNanotubes, CarbonNeoplasmsQuantum DotsSurface PropertiesTransferrinAntineoplastic AgentsDeoxycytidineDoxorubicinDrug CarriersFluorescent DyesFolic AcidGemcitabineHyaluronic AcidNanotubes, CarbonTransferrincarbon dotscarbon nanotubesdoxorubicindrug deliveryfolic acidgemcitabinehyaluronantransferrin

Identifiers

PMID29439409
PMCPMC6017112

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.