Evidence map›Paper›PMID 29439396›Full record

ArticleMolecules (Basel, Switzerland)2018

Functional Magnetic Mesoporous Silica Microparticles Capped with an Azo-Derivative: A Promising Colon Drug Delivery Device.

Adrián H Teruel, Carmen Coll, Ana M Costero, Daniel Ferri, Margarita Parra, Pablo Gaviña, Marta González-Álvarez, Virginia Merino, M Dolores Marcos, Ramón Martínez-Máñez and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Adrián H TeruelInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. adherte@upv.es.ORCID 0000-0001-5749-7941
Carmen CollInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. macolme1@upvnet.upv.es.
Ana M CosteroInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. ana.costero@uv.es.ORCID 0000-0001-9640-1148
Daniel FerriInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. daniel.ferri@uv.es.
Margarita ParraInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. margarita.parra@uv.es.
Pablo GaviñaInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. pablo.gavina@uv.es.
Marta González-ÁlvarezEngineering Department. Pharmacy and Pharmaceutical Technology Section, Miguel Hernandez University, 03550 Alicante, Spain. marta.gonzalez@umh.es.
Virginia MerinoInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. Virginia.merino@uv.es.
M Dolores MarcosInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. mmarcos@qim.upv.es.
Ramón Martínez-MáñezInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. rmaez@qim.upv.es.ORCID 0000-0001-5873-9674
Félix SancenónInteruniversity Research Institute for Molecular Recognition and Technological Development (IDM), Polytechnic University of Valencia, University of Valencia, 46100 Valencia, Spain. fsanceno@upvnet.upv.es.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Magnetic micro-sized mesoporous silica particles were used for the preparation of a gated material able to release an entrapped cargo in the presence of an azo-reducing agent and, to some extent, at acidic pH. The magnetic mesoporous microparticles were loaded with safranin O and the external surface was functionalized with an azo derivative

Indexed as

Azo CompoundsChloridesColonDithioniteDrug CarriersDrug LiberationFerric CompoundsFerrous CompoundsHumansHydrogen-Ion ConcentrationHydrolysisMagneticsMicrospheresNanoparticlesOxidation-ReductionPhenazinesAzo CompoundsChloridesDithioniteDrug Carriersferric chlorideFerric Compoundsferrous chlorideFerrous CompoundsPhenazinessafranine TSilicon Dioxideazo derivativesazo reductorcolon releasemagnetic mesoporous silicapH triggered

Identifiers

PMID29439396
PMCPMC6017295

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.