ArticleRestorative neurology and neuroscience2018
Effects of posture and coactivation on corticomotor excitability of ankle muscles.
Article in Restorative neurology and neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 14 citations in OpenAlex.
- High-Intensity Gait Training With Functional Electrical Stimulation Enhances Corticospinal Excitability of Paretic Ankle Muscles in Individuals Post-Stroke.Neural plasticity · 2025Trial
- Effects of stepping practice and functional electrical stmulation on neuromotor excitability in able bodied young adults.Experimental brain research · 2025Article
- Article
- Corticospinal activity during a single-leg stance in people with chronic ankle instability.Journal of sport and health science · 2022Article
- Young adults perceive small disturbances to their walking balance even when distracted.Gait & posture · 2022Article
- Standing Neurophysiological Assessment of Lower Extremity Muscles Post-Stroke.Journal of visualized experiments : JoVE · 2021Article
- Probing the Brain-Body Connection Using Transcranial Magnetic Stimulation (TMS): Validating a Promising Tool to Provide Biomarkers of Neuroplasticity and Central Nervous System Function.Brain sciences · 2021Article
- Temporal Profile of Descending Cortical Modulation of Spinal Excitability: Group and Individual-Specific Effects.Frontiers in integrative neuroscience · 2021Article
- Integration of Convergent Sensorimotor Inputs Within Spinal Reflex Circuits in Healthy Adults.Frontiers in human neuroscience · 2020Article
- Agonist-Antagonist Coactivation Enhances Corticomotor Excitability of Ankle Muscles.Neural plasticity · 2019Article
- Biomechanical and neural correlates of FastFES versus Fast gait training in individuals post stroke: a randomized control trial study protocol.Frontiers in neurologyArticle
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundThe use of transcranial magnetic stimulation (TMS) to evaluate corticomotor excitability of lower limb (LL) muscles can provide insights about neuroplasticity mechanisms underlying LL rehabilitation. However, to date, a majority of TMS studies have focused on upper limb muscles. Posture-related activation is an important under-investigated factor influencing corticomotor excitability of LL muscles.
objectiveThe purpose of this study was to evaluate effects of posture and background activation on corticomotor excitability of ankle muscles.
methodsFourteen young neurologically-unimpaired participants (26.1±4.1 years) completed the study. TMS-evoked motor evoked potentials (MEPs) were recorded from the tibialis anterior (TA) and soleus during 4 conditions - standing, standing coactivation, sitting, and sitting coactivation. TA and soleus MEP amplitudes were compared during: (1) standing versus sitting;(2) standing coactivation (standing while activating both TA and soleus) versus sitting coactivation; and (3) standing coactivation versus standing. For each comparison, background EMG for TA and soleus were matched. Trial-to-trial coefficient of variation of MEP amplitude and coil-positioning errors were additional dependent variables.
resultsNo differences were observed in TA or soleus MEP amplitudes during standing versus sitting. Compared to sitting coactivation, larger MEPs were observed during standing coactivation for soleus but not TA. Compared to standing, the standing coactivation task demonstrated larger MEPs and reduced trial-to-trial MEP variability.
conclusionOur findings suggest that incorporation of measurements in standing in future TMS studies may provide novel insights into neural circuits controlling LL muscles. Standing and standing coactivation tasks may be beneficial for obtaining functionally-relevant neuroplasticity assessments of LL musculature.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.