Evidence map›Paper›PMID 29439167›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2018

Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance.

Samantha Ing-Esteves, Dimitar Kostadinov, Julie Marocha, Anson D Sing, Kezia S Joseph, Mallory A Laboulaye, Joshua R Sanes, Julie L Lefebvre

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 109 citations in OpenAlex.

  1. Article
  2. WAVE2 and REST/NRSF Regulate Clustered Gene Expression by Maintaining Heterochromatin Organization.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  3. Protocadherin 9 Promotes Cell Survival of Different Bipolar Cell Types in the Developing Mouse Retina.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2026
    Article
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  14. The Interaction Between Family Functioning and thePsychology research and behavior management · 2025
    Article
  15. Article
  16. Article
  17. The Role of Protocadherin γ in Adult Sensory Neurons and Skin Reinnervation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
  18. Visualization ofProceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Visualization ofiScience · 2023
    Article
  20. A Unique Role for Protocadherin γC3 in Promoting Dendrite Arborization through an Axin1-Dependent Mechanism.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Samantha Ing-EstevesProgram for Neurosciences and Mental Health, Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada and.
Dimitar KostadinovDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138.ORCID 0000-0001-7548-2209
Julie MarochaProgram for Neurosciences and Mental Health, Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada and.
Anson D SingProgram for Neurosciences and Mental Health, Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada and.ORCID 0000-0002-1122-9527
Kezia S JosephProgram for Neurosciences and Mental Health, Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada and.ORCID 0000-0002-9241-3069
Mallory A LaboulayeDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138.
Joshua R SanesDepartment of Molecular and Cellular Biology and Center for Brain Science, Harvard University, Cambridge, Massachusetts 02138.ORCID 0000-0001-8926-8836
Julie L LefebvreProgram for Neurosciences and Mental Health, Hospital for Sick Children, Department of Molecular Genetics, University of Toronto, Toronto, Ontario M5G 0A4, Canada and julie.lefebvre@sickkids.ca.ORCID 0000-0002-3110-860X
Harvard University · USUniversity of Toronto · CA

Funding

RESEARCH TRAINING IN VISUAL NEUROSCIENCET32EY007110 · NEI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI BORN, RICHARD T · 1988 to 2023
$4.1M
Combinatorial roles of cadherins in retinal circuit assembly.R01EY022073 · NEI · HARVARD UNIVERSITY · PI SANES, JOSHUA R · 2012 to 2020
$3.7M
Pcdhgs pattern starburst amacrine dendrites and direction selective circuitsF31NS078893 · NINDS · HARVARD MEDICAL SCHOOL · PI KOSTADINOV, DIMITAR · 2012 to 2013
$62k
NEI NIH HHS R01 EY022073NEI NIH HHS T32 EY007110NINDS NIH HHS F31 NS078893
6 · The paper itself

Abstract

The clustered protocadherins (Pcdhs) comprise 58 cadherin-related proteins encoded by three tandemly arrayed gene clusters,

Indexed as

Amacrine CellsAnimalsAxonsCadherin Related ProteinsCadherinsCell SurvivalCerebellumDendritesFemaleGene DeletionMaleMiceMice, Inbred C57BLMutationNeurogenesisPurkinje CellsCadherin Related ProteinsCadherinsGamma-protocadherinsapoptosisdendriteneurite developmentprotocadherinretinaself-avoidance

Identifiers

PMID29439167
PMCPMC5852656
OpenAlexW2786541519

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.