Evidence map›Paper›PMID 29438963›Full record

ArticleArchives of disease in childhood2018

Health professionals' and coroners' views on less invasive perinatal and paediatric autopsy: a qualitative study.

Celine Lewis, Melissa Hill, Owen J Arthurs, John C Hutchinson, Lyn S Chitty, Neil Sebire

Open access · hybridAbstract read
In one paragraph

Article in Archives of disease in childhood, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Minimally invasive autopsy - endoscopic approach to post-mortem diagnostics.Wideochirurgia i inne techniki maloinwazyjne = Videosurgery and other miniinvasive techniques · 2024
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  9. Understanding the complexities of unexplained stillbirth in sub-Saharan Africa: a mixed-methods study.BJOG : an international journal of obstetrics and gynaecology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Celine LewisNorth East Thames Regional Genetics Service, Great Ormond Street Hospital, NHS Foundation Trust, London, UK.ORCID 0000-0001-7169-1521
Melissa HillNorth East Thames Regional Genetics Service, Great Ormond Street Hospital, NHS Foundation Trust, London, UK.
Owen J ArthursGenetics and Genomic Medicine, The UCL Great Ormond Street Institute of Child Health, London, UK.
John C HutchinsonGenetics and Genomic Medicine, The UCL Great Ormond Street Institute of Child Health, London, UK.
Lyn S ChittyNorth East Thames Regional Genetics Service, Great Ormond Street Hospital, NHS Foundation Trust, London, UK.
Neil SebireGenetics and Genomic Medicine, The UCL Great Ormond Street Institute of Child Health, London, UK.
Great Ormond Street Hospital · GB

Funding

Department of Health 14/168/02Department of Health CDF-2017-10-037Department of Health HTA/14/168/02Department of Health NIHR-CS-012-002
6 · The paper itself

Abstract

objectiveTo assess health professionals' and coroners' attitudes towards non-minimally and minimally invasive autopsy in the perinatal and paediatric setting.

methodsA qualitative study using semistructured interviews. Data were analysed thematically.

resultsTwenty-five health professionals (including perinatal/paediatric pathologists and anatomical pathology technologists, obstetricians, fetal medicine consultants and bereavement midwives, intensive care consultants and family liaison nurses, a consultant neonatologist and a paediatric radiologist) and four coroners participated. Participants viewed less invasive methods of autopsy as a positive development in prenatal and paediatric care that could increase autopsy rates. Several procedural and psychological benefits were highlighted including improved diagnostic accuracy in some circumstances, potential for faster turnaround times, parental familiarity with imaging and laparoscopic approaches, and benefits to parents and faith groups who object to invasive approaches. Concerns around the limitations of the technology such not reaching the same levels of certainty as full autopsy, unsuitability of imaging in certain circumstances, the potential for missing a diagnosis (or misdiagnosis) and de-skilling the workforce were identified. Finally, a number of implementation issues were raised including skills and training requirements for pathologists and radiologists, access to scanning equipment, required computational infrastructure, need for a multidisciplinary approach to interpret results, cost implications, equity of access and acceptance from health professionals and hospital managers.

conclusionHealth professionals and coroners viewed less invasive autopsy as a positive development in perinatal and paediatric care. However, to inform implementation a detailed health economic analysis and further exploration of parental views, particularly in different religious groups, are required.

Indexed as

AttitudePerinatal DeathAutopsyClinical CompetenceCoroners and Medical ExaminersCosts and Cost AnalysisDiagnostic ImagingHealth PersonnelHumansInfant, NewbornInterviews as TopicParentsPathology, ClinicalQualitative ResearchRadiologyReligionautopsyless invasivepaediatricperinatalpost mortem

Identifiers

PMID29438963
PMCPMC5965355
OpenAlexW2787531851

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.