Evidence map›Paper›PMID 29438814›Full record

ArticleMicrovascular research2018

Inter-visit variability of conjunctival microvascular hemodynamic measurements in healthy and diabetic retinopathy subjects.

Maziyar M Khansari, Michael Tan, Preny Karamian, Mahnaz Shahidi

Open access · hybridAbstract read
In one paragraph

Article in Microvascular research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 18 citations in OpenAlex.

  1. Conjunctival Venular Hemodynamic Biomarkers in Glaucoma.Translational vision science & technology · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Maziyar M KhansariDepartment of Ophthalmology, University of Southern California, CA, USA; Laboratory of Neuro Imaging, USC Stevens Neuroimaging and Informatics Institute, Keck School of Medicine, University of Southern California, CA, USA.
Michael TanDepartment of Ophthalmology & Visual Sciences, University of Illinois at Chicago, IL, USA.
Preny KaramianDepartment of Ophthalmology, University of Southern California, CA, USA.
Mahnaz ShahidiDepartment of Ophthalmology, University of Southern California, CA, USA. Electronic address: mshahidi@usc.edu.
University of Southern California · USUniversity of Illinois Chicago · US

Funding

Translational Core for Therapeutic and Diagnostic DevelopmentP30EY001792 · NEI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AAKALU, VINAY · 1985 to 2025
$14.8M
Ocular Biomarkers of Microvascular, Neural and Metabolic Function in DiabetesDP3DK104393 · NIDDK · UNIVERSITY OF SOUTHERN CALIFORNIA · PI SHAHIDI, MAHNAZ · 2014 to 2014
$1.5M
NEI NIH HHS P30 EY001792NIDDK NIH HHS DP3 DK104393
6 · The paper itself

Abstract

Conjunctival microcirculation imaging provides a non-invasive means for detecting hemodynamic alterations due to systemic and ocular diseases. However, reliable longitudinal monitoring of hemodynamic changes due to disease progression requires establishment of measurement variability over time. The purpose of the current study was to determine inter-visit variability of conjunctival microvascular hemodynamic measurements in non-diabetic control (NC, N = 7) and diabetic retinopathy (DR, N = 10) subjects. Conjunctival microvascular imaging was performed during 2 visits, which were 17 ± 12 weeks apart. Images were analyzed to determine vessel diameter (D), axial blood velocity (V), blood flow (Q), wall shear rate (WSR) and wall shear stress (WSS). The inter-visit variability was determined based on mean inter-visit differences. In NC, inter-visit variability of D, V, Q, WSR and WSS were 0.2 ± 0.5 μm, -0.01 ± 0.16 mm/s, -8 ± 46 pl/s, -3 ± 46 s

Indexed as

HemodynamicsMicrocirculationSlit Lamp MicroscopyAdolescentAdultAgedBlood Flow VelocityCase-Control StudiesConjunctivaDiabetic RetinopathyDisease ProgressionFemaleHealthy VolunteersHumansMaleMicrovesselsConjunctival microvasculatureDiabetic retinopathyInter-visit variabilityMicrocirculationMicrovascular hemodynamics

Identifiers

PMID29438814
PMCPMC5992619
OpenAlexW2789531007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.