ArticleThe American journal of sports medicine2018
Twenty-Year Follow-up Study Comparing Operative Versus Nonoperative Treatment of Anterior Cruciate Ligament Ruptures in High-Level Athletes.
Article in The American journal of sports medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 5 of them syntheses that pooled it.
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Who cites it
68 citing papers in PubMed, 5 syntheses or guidelines pooled it, 126 citations in OpenAlex.
- The Long-term Radiographic Fate of the Chronically ACL-Deficient Knee: A Systematic Review and Meta-analysis of Matched Cohort Studies.The American journal of sports medicine · 2026Pooled it
- No Difference in Return-to-Sport Rate or Activity Level in People with Anterior Cruciate Ligament (ACL) Injury Managed with ACL Reconstruction or Rehabilitation Alone: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2025Pooled it
- Pooled it
- "Cost-effectiveness of ACL treatment is dependent on age and activity level: a systematic review".Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Pooled it
- Operative Versus Conservative Treatment of Anterior Cruciate Ligament Rupture.Deutsches Arzteblatt international · 2018Pooled it
- Evidence of ACL healing on MRI following ACL rupture treated with rehabilitation alone may be associated with better patient-reported outcomes: a secondary analysis from the KANON trial.British journal of sports medicine · 2023Trial
- Early surgical reconstruction versus rehabilitation with elective delayed reconstruction for patients with anterior cruciate ligament rupture: COMPARE randomised controlled trial.BMJ (Clinical research ed.) · 2021Trial
- Reconstruction After an Anterior Cruciate Ligament Injury Does Not Reduce the Osteoarthritis Risk But Lowers the Total Knee Arthroplasty Rate: A Systematic Review and Meta-analysis.Orthopaedic journal of sports medicine · 2026Review
- Article
- Surgical Versus Rehabilitation-First Management Strategies After ACL Injury: Persisting Uncertainty over Long-Term Outcomes-A Systematic Search and Narrative Synthesis of Randomized Trial Cohorts.Healthcare (Basel, Switzerland) · 2026Review
- Cellular and molecular landscapes of inflammation in anterior cruciate ligament rupture patients are independent on concurrent meniscal injury.Arthritis research & therapy · 2026Article
- Reliability of Semi-Automated Volumetric Quantification of Knee Effusion Using MRI After Acl Injury.The Iowa orthopaedic journal · 2026Observational
- Article
- High posterior tibial slope is associated with higher failure rates in nonoperative management of primary anterior cruciate ligament injury.Journal of experimental orthopaedics · 2025Article
- Long-term results of anterior cruciate ligament reconstruction using the medial third of the patellar tendon.Journal of experimental orthopaedics · 2025Article
- Physical Activity and Sedentary Behavior Differ by Sex during the First 6 Months after Anterior Cruciate Ligament Reconstruction.Medicine and science in sports and exercise · 2025Observational
- Article
- Nonoperative Treatment of Anterior Cruciate Ligament Tears With 5-Year Follow-up.Orthopaedic journal of sports medicine · 2025Article
- Clinical Outcome of Femoral Suspensory Fixation for Anterior Cruciate Ligament (ACL) Reconstruction.Cureus · 2025Article
- Efficacy of a Squat Visual Biofeedback Program After ACL Reconstruction: Protocol for a Prospective, Parallel, Randomized Controlled Trial.International journal of sports physical therapy · 2025Article
8 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAn anterior cruciate ligament (ACL) rupture has major consequences at midterm follow-up, with an increasing chance of developing an old knee in a young patient. The long-term (≥20 years) effects of the operative and nonoperative treatment of ACL ruptures are still unclear. PURPOSE: To compare the long-term treatment outcomes of operative versus nonoperative treatment of ACL ruptures in high-level athletes. STUDY
designCohort study; Level of evidence, 2.
methodsFifty patients with an ACL rupture were eligible for participation, and they were treated either nonoperatively (n = 25) in 1992, consisting of structured rehabilitation and lifestyle adjustments, or operatively (n = 25) between 1994 and 1996 with an arthroscopic transtibial bone-patellar tendon-bone technique. The patients in the nonoperative group were drawn from those who responded well to 3 months of nonoperative treatment, whereas the patients in the operative group were drawn from those who had persistent instability after 3 months of nonoperative treatment. Both groups were pair-matched and assessed at 10- and 20-year follow-up regarding radiological knee osteoarthritis, functional outcomes (Lysholm, International Knee Documentation Committee [IKDC], Tegner, Knee injury and Osteoarthritis Outcome Score), meniscal status, and knee stability (KT-1000 arthrometer, pivot-shift test, Lachman test, 1-legged hop test).
resultsAll 50 patients (100%) were included in the current study for follow-up. After 20 years, we found knee osteoarthritis in 80% of the operative group compared with 68% of the nonoperative group ( P = .508). There was no difference between groups regarding functional outcomes and meniscectomy performed. The median IKDC subjective score was 81.6 (interquartile range [IQR], 59.8-89.1) for the operative group and 78.2 (IQR, 61.5-92.0) for the nonoperative group ( P = .679). Regarding the IKDC objective score, 21 patients (84%) in the operative group had a normal or near normal score (A and B) compared with 5 patients (20%) in the nonoperative group ( P < .001). The pivot-shift test finding was negative in 17 patients (68%) versus 3 patients (13%) for the operative and nonoperative groups, respectively ( P < .001), and the Lachman test finding was negative in 12 patients (48%) versus 1 patient (4%), respectively ( P = .002).
conclusionIn this retrospective pair-matched follow-up study, we found that after 20-year follow-up, there was no difference in knee osteoarthritis between operative versus nonoperative treatment when treatment was allocated on the basis of a patient's response to 3 months of nonoperative treatment. Although knee stability was better in the operative group, it did not result in better subjective and objective functional outcomes.
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