Evidence map›Paper›PMID 29438416›Full record

ArticlePloS one2018

Diastereoselective synthesis of chiral 1,3-cyclohexadienals.

Aitor Urosa, Ignacio E Tobal, Ángela P de la Granja, M Carmen Capitán, R F Moro, Isidro S Marcos, Narciso M Garrido, Francisca Sanz, Emilio Calle, David Díez

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Aitor UrosaDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
Ignacio E TobalDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
Ángela P de la GranjaDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
M Carmen CapitánDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
R F MoroDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
Isidro S MarcosDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
Narciso M GarridoDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
Francisca SanzServicio de Difracción de Rayos X, Universidad de Salamanca, Salamanca, Spain.
Emilio CalleDepartamento de Química Física, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.
David DíezDepartamento de Química Orgánica, Facultad de Ciencias Químicas, Universidad de Salamanca, Salamanca, Spain.ORCID 0000-0002-7261-8454

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A novel approach to the production of chiral 1,3-cyclohexadienals has been developed. The organocatalysed asymmetric reaction of different β-disubstituted-α,β-unsaturated aldehydes with a chiral α,β-unsaturated aldehyde in the presence of a Jørgensen-Hayashi organocatalyst provides easy and stereocontrolled access to the cyclohexadienal backbone. This method allows for the synthesis of potential photoprotective chiral 1,3-cyclohexadienals and extra extended conjugation compounds in a simple manner.

Indexed as

AldehydesCarbon-13 Magnetic Resonance SpectroscopyCrystallography, X-RayCyclohexenesModels, MolecularProton Magnetic Resonance SpectroscopySpectrometry, Mass, Electrospray IonizationStereoisomerism1,3-cyclohexadieneAldehydesCyclohexenes

Identifiers

PMID29438416
PMCPMC5810990

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.