ArticlePloS one2018
Prenatal exposure to preeclampsia is associated with accelerated height gain in early childhood.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 18 citations in OpenAlex.
- Cord Blood Proteomic Profiles, Birth Weight, and Early Life Growth Trajectories.JAMA network open · 2024Article
- The impact of partner's behaviour on pregnancy related outcomes and safe child-birth in Pakistan.BMC pregnancy and childbirth · 2023Article
- A review of infant growth and psychomotor developmental outcomes after intrauterine exposure to preeclampsia.BMC pediatrics · 2022Review
- Nanomaterial Inhalation During Pregnancy Alters Systemic Vascular Function in a Cyclooxygenase-Dependent Manner.Toxicological sciences : an official journal of the Society of Toxicology · 2022Article
- Association of hypertensive disorders of pregnancy with infant growth in the first 36 months of life.European journal of pediatrics · 2022Article
- Hypertensive Disorders during Pregnancy and Anthropometric Measurement of Children up to 7 Years of Age: The Hokkaido Birth Cohort Study in Japan.International journal of environmental research and public health · 2021Article
- Association of preeclampsia with anthropometric measures and blood pressure in Indian children.PloS one · 2020Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPreeclampsia is associated with low birth weight, both because of increased risks of preterm and of small-for-gestational-age (SGA) births. Low birth weight is associated with accelerated childhood height gain and cardiovascular diseases later in life. The aim was to investigate if prenatal exposure to preeclampsia is associated with accelerated childhood height gain, also after adjustments for SGA-status and gestational age at birth.
methodsIn a cohort of children prenatally exposed to preeclampsia (n = 865) or unexposed (n = 22,898) we estimated height gain between birth and five years of age. The mean difference in height gain between exposed and unexposed children was calculated and adjustments were done with linear regression models.
resultsChildren exposed to preeclampsia were on average born shorter than unexposed. Exposed children grew on average two cm more than unexposed from birth to five years of age. After adjustments for maternal characteristics including socioeconomic factors, height, body mass index (BMI) and diabetes, as well as for parents smoking habits, infant's breastfeeding and childhood obesity, the difference was 1.6 cm (95% CI 1.3-1.9 cm). Further adjustment for SGA birth only slightly attenuated this estimate, but adjustment for gestational age at birth decreased the estimate to 0.5 cm (95% CI 0.1-0.7 cm).
conclusionPrenatal exposure to preeclampsia is associated with accelerated height gain in early childhood. The association seemed independent on SGA-status, but partly related to shorter gestational age at birth.
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