ArticlePloS one2018
Predicting mortality in extremely low birth weight infants: Comparison between gestational age, birth weight, Apgar score, CRIB II score, initial and lowest serum albumin levels.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Neonatal death prediction scores: a systematic review and meta-analysis.BMJ paediatrics open · 2024Pooled it
- Comparing mortality risk models in VLBW and preterm infants: systematic review and meta-analysis.Journal of perinatology : official journal of the California Perinatal Association · 2020Pooled it
- Survival, Mortality Predictors, and Morbidity in Extremely Low Birth Weight Neonates: A Retrospective Cohort Study at a Tertiary Hospital in the Eastern Cape, South Africa.Children (Basel, Switzerland) · 2026Article
- Impact of respiratory support on time to achieve full oral feeding in very low birth weight infants: a retrospective study.Frontiers in pediatrics · 2026Article
- Incidence of low birth weight among newborns delivered in health facilities in the Volta Region, 2019-2023.BMC pregnancy and childbirth · 2025Article
- Neonatologist staffing is related to the inter-hospital variation of risk-adjusted mortality of very low birth weight infants in Korea.Scientific reports · 2024Article
- Is It Possible to Prevent the Thanatogenetic Processes in Premature Babies?Clinics and practice · 2024Article
- Association Between Albumin Levels and Neonatal Acute Respiratory Distress Syndrome in Newborn Pneumoniae.Journal of inflammation research · 2024Article
- A comparative analysis of APGAR score and the gold standard in the diagnosis of birth asphyxia at a tertiary health facility in Kenya.PloS one · 2023Article
- Predictive factors for extubation success in very low and extremely low birth weight preterm infants.Canadian journal of respiratory therapy : CJRT = Revue canadienne de la therapie respiratoire : RCTR · 2023Article
- Do maternal albumin levels affect post-operative complications after cesarean delivery?BMC pregnancy and childbirth · 2022Article
- Comparison of CRIB-II with SNAPPE-II for predicting survival and morbidities before hospital discharge in neonates with gestation ≤ 32 weeks: a prospective multicentric observational study.European journal of pediatrics · 2022Observational
- Effect of levothyroxine supplementation in extremely low birth weight infants with transient hypothyroxinemia of prematurity.Scientific reports · 2022Article
- Outcomes of laparotomy in preterm infants with extremely low operative weight (< 1000 g).Pediatric surgery international · 2022Article
- Maternal-Neonatal Serum Albumin Level and Neonatal Respiratory Distress Syndrome in Late-Preterm Infants.Frontiers in pediatrics · 2021Article
- Association between Adherence with Recommended Antenatal Care in Low-Risk, Uncomplicated Pregnancy, and Maternal and Neonatal Adverse Outcomes: Evidence from Italy.International journal of environmental research and public health · 2020Article
- Determinants of Low Birth Weight in Ghana: Does Quality of Antenatal Care Matter?Maternal and child health journal · 2020Article
- Outcome of extremely low birth weight (ELBW) infants from a birth cohort (2013-2018) in a tertiary care unit in North India.Journal of perinatology : official journal of the California Perinatal Association · 2020Article
- Article
- Incidence and severity of transient hypothyroxinaemia of prematurity associated with survival without composite morbidities in extremely low birth weight infants.Scientific reports · 2019Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We explored GA, BW, Apgar score, CRIB II score, and serum albumin levels as univariate predictors of mortality in extremely low birth weight infants. Medical records of 564 extremely low birth weight infants were reviewed retrospectively. The infants were grouped as survivors (group I), expired ≤ 7th postnatal day (group II), and expired > 7th postnatal day (group III). The predictive value for mortality of gestational age, birth weight, Apgar scores at 1 and 5 min, clinical risk index for babies II score, and first and lowest serum albumin levels was assessed by calculating the associated area under the curve (AUC) in receiver operating characteristic (ROC) curves. The overall survival and mortality rates of groups I, II, and III were 81.0% (457/564), 7.6% (43/564), and 11.4% (64/564), respectively. Birth weight, Apgar scores at 1 and 5 min, and first serum albumin levels were significantly higher, while the clinical risk index for babies II score was significantly lower in group I when compared to groups II and III. Gestational age and lowest serum albumin level in group I were significantly higher than group III, but not group II. However, gestational age, birth weight, and clinical risk index for babies II score showed gestational age dependent variations regardless of survival or mortality. Apgar score at 5 min (0.756) and lowest serum albumin level (0.771) demonstrated the highest AUC of the ROC curve in predicting mortality in group II and III, respectively. In conclusion, Apgar score at 5 min and lowest serum albumin level were the most effective predictors for mortality in extremely low birth weight infants during ≤ 7th and > 7th postnatal days, respectively.
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