Evidence map›Paper›PMID 29438297›Full record

ArticleBioengineering (Basel, Switzerland)2018

Fenofibrate Nanocrystals Embedded in Oral Strip-Films for Bioavailability Enhancement.

Bhavesh D Kevadiya, Manish Barvaliya, Lu Zhang, Ashish Anovadiya, Harshad Brahmbhatt, Parimal Paul, Chandrabhanu Tripathi

Abstract read
In one paragraph

Article in Bioengineering (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
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  7. Neurotheranostics as personalized medicines.Advanced drug delivery reviews · 2019
    Review
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Bhavesh D KevadiyaDepartment of Chemical, Biological and Pharmaceutical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA. bhavesh.kevadiya@unmc.edu.ORCID 0000-0003-4016-132X
Manish BarvaliyaDepartment of Pharmacology, Government Medical College, Bhavnagar 364002, Gujarat, India. drmanishbarvaliya@gmail.com.
Lu ZhangDepartment of Chemical, Biological and Pharmaceutical Engineering, New Jersey Institute of Technology, Newark, NJ 07102, USA. lz74@njit.edu.
Ashish AnovadiyaDepartment of Pharmacology, Government Medical College, Bhavnagar 364002, Gujarat, India. ashishanovadiya@yahoo.com.
Harshad BrahmbhattAnalytical Discipline and Centralized Instrument Facility, The Academy of Scientific & Innovative Research (AcSIR), Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research (CSIR), G.B. Marg, Bhavnagar 364002, Gujarat, India. harshadb@csmcri.org.
Parimal PaulAnalytical Discipline and Centralized Instrument Facility, The Academy of Scientific & Innovative Research (AcSIR), Central Salt and Marine Chemicals Research Institute, Council of Scientific and Industrial Research (CSIR), G.B. Marg, Bhavnagar 364002, Gujarat, India. ppaul@csmcri.org.
Chandrabhanu TripathiDepartment of Pharmacology, Government Medical College, Bhavnagar 364002, Gujarat, India. cbtripathi@yahoo.co.in.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of the present study was to make a fenofibrate (FNB) nanocrystal (NC) by wet media milling, characterizations and formulates into oral strip-films (OSFs). Mechanical properties, redispersion study, and solid-state characterizations results suggested that reduction of drug crystal size at nanoscale and incorporation into OSFs does not affect the solid-state properties of the drug.

Indexed as

bioavailabilityfenofibratemedia millingpharmacokineticsUV imaging

Identifiers

PMID29438297
PMCPMC5874882

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.