Evidence map›Paper›PMID 29438294›Full record

ArticleViruses2018

First Diagnosed Case of Camelpox Virus in Israel.

Oran Erster, Sharon Melamed, Nir Paran, Shay Weiss, Yevgeny Khinich, Boris Gelman, Aharon Solomony, Orly Laskar-Levy

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Frontiers in veterinary science · 2020
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Oran ErsterDivision of Virology, Kimron Veterinary Institute, P.O. Box 12, Beit Dagan 50250, Israel. Orane@moag.gov.il.
Sharon MelamedDepartment of Infectious Diseases, IIBR P.O. Box 19, Ness Ziona 74100, Israel. sharonm@iibr.gov.il.
Nir ParanDepartment of Infectious Diseases, IIBR P.O. Box 19, Ness Ziona 74100, Israel. nirp@iibr.gov.il.
Shay WeissDepartment of Infectious Diseases, IIBR P.O. Box 19, Ness Ziona 74100, Israel. shayw@iibr.gov.il.
Yevgeny KhinichDivision of Virology, Kimron Veterinary Institute, P.O. Box 12, Beit Dagan 50250, Israel. vaccine@moag.gov.il.
Boris GelmanDivision of Virology, Kimron Veterinary Institute, P.O. Box 12, Beit Dagan 50250, Israel. Borisg@moag.gov.il.
Aharon SolomonyNegev Veterinary Bureau, Israeli Veterinary Services, Binyamin Ben Asa 1, Be'er Sheba 84102, Israel. Aharons@moag.gov.il.
Orly Laskar-LevyDepartment of Infectious Diseases, IIBR P.O. Box 19, Ness Ziona 74100, Israel. orlyl@iibr.gov.il.
Israel Institute for Biological Research · ILVeterinary Services and Animal Health

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

An outbreak of a disease in camels with skin lesions was reported in Israel during 2016. To identify the etiological agent of this illness, we employed a multidisciplinary diagnostic approach. Transmission electron microscopy (TEM) analysis of lesion material revealed the presence of an orthopox-like virus, based on its characteristic brick shape. The virus from the skin lesions successfully infected chorioallantoic membranes and induced cytopathic effect in Vero cells, which were subsequently positively stained by an orthopox-specific antibody. The definite identification of the virus was accomplished by two independent qPCR, one of which was developed in this study, followed by sequencing of several regions of the viral genome. The qPCR and sequencing results confirmed the presence of camelpox virus (CMLV), and indicated that it is different from the previously annotated CMLV sequence available from GenBank. This is the first reported case of CMLV in Israel, and the first description of the isolated CMLV subtype.

Indexed as

OrthopoxvirusAnimalsCell LineChick EmbryoChlorocebus aethiopsCytopathogenic Effect, ViralDisease OutbreaksFemaleHumansIsraelPhylogenyPopulation SurveillancePoxviridae InfectionsVero Cellscamelpox viruschorioallantoic membraneImmunofluorescence assay (IFA)orthopoxvirusPCRtransmission electron microscopy

Identifiers

PMID29438294
PMCPMC5850385
OpenAlexW2790936550

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.