Evidence map›Paper›PMID 29438285›Full record

ArticleGenes2018

MicroRNA-31 and MicroRNA-155 Are Overexpressed in Ulcerative Colitis and Regulate IL-13 Signaling by Targeting Interleukin 13 Receptor α-1.

Markus Gwiggner, Rocio T Martinez-Nunez, Simon R Whiteoak, Victor P Bondanese, Andy Claridge, Jane E Collins, J R Fraser Cummings, Tilman Sanchez-Elsner

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genes, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Review
  5. Efficacy ofNutrients · 2024
    Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. miRNA Molecules-Late Breaking Treatment for Inflammatory Bowel Diseases?International journal of molecular sciences · 2023
    Review
  12. Review
  13. MicroRNAs in Inflammatory Bowel Disease and Its Complications.International journal of molecular sciences · 2022
    Review
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Markus GwiggnerClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. markus.gwiggner@uhs.nhs.uk.
Rocio T Martinez-NunezClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. r.t.martinez-nunez@soton.ac.uk.ORCID 0000-0003-2507-4738
Simon R WhiteoakClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. srw299@doctors.org.uk.
Victor P BondaneseClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. victorpaky@yahoo.com.
Andy ClaridgeClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. andrew.claridge1@nhs.net.
Jane E CollinsClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. j.e.collins@soton.ac.uk.
J R Fraser CummingsUniversity Hospital Southampton NHS FT, Tremona Road, Southampton SO16 6YD, UK. fraser.cummings@uhs.nhs.uk.
Tilman Sanchez-ElsnerClinical and Experimental Sciences, Sir Henry Wellcome Laboratories, University of Southampton School of Medicine, Southampton SO17 1BJ, UK. t.sanchez-elsner@soton.ac.uk.
University of Southampton · GBUniversity Hospital Southampton NHS Foundation Trust · GBKing's College London · GB

Funding

Medical Research Council MR/K001035/1
6 · The paper itself

Abstract

Interleukin-13 (IL-13) is an important Type 2 T helper (Th2) cytokine, controlling biological functions in epithelium and has been linked to asthma, atopic dermatitis and ulcerative colitis (UC). Interleukin-13 signals through IL-13 receptor α-1 (

Indexed as

epitheliumgutinflammationinterleukin-13microRNAsulcerative colitis

Identifiers

PMID29438285
PMCPMC5852581
OpenAlexW2787984929

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.