Evidence map›Paper›PMID 29437945›Full record

ArticleThe European respiratory journal2018

A comparison of linezolid lung tissue concentrations among patients with drug-resistant tuberculosis.

Russell R Kempker, M Tobias Heinrichs, Ketino Nikolaishvili, Irina Sabulua, Nino Bablishvili, Shota Gogishvili, Zaza Avaliani, Brent P Little, Adam Bernheim, Hartmut Derendorf and 3 more

Abstract readLetter
In one paragraph

Article in The European respiratory journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Mycobacterium tuberculosis sterilizing activity of faropenem, pyrazinamide and linezolid combination and failure to shorten the therapy duration.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
    Article
  5. Article
  6. Review
  7. Article
  8. Linezolid-induced pure red cell aplasia: a case report and literature review.The Journal of international medical research · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Russell R KempkerDivision of Infectious Diseases, Dept of Medicine, Emory University School of Medicine, Atlanta, GA, USA rkempke@emory.edu.
M Tobias HeinrichsUniversity of Florida, College of Pharmacy, Gainesville, FL, USA.
Ketino NikolaishviliNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Irina SabuluaNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Nino BablishviliNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Shota GogishviliNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Zaza AvalianiNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Brent P LittleDept of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Adam BernheimDept of Radiology and Imaging Sciences, Emory University School of Medicine, Atlanta, GA, USA.
Hartmut DerendorfUniversity of Florida, College of Pharmacy, Gainesville, FL, USA.
Henry M BlumbergDivision of Infectious Diseases, Dept of Medicine, Emory University School of Medicine, Atlanta, GA, USA.
Sergo VashakidzeNational Center for Tuberculosis and Lung Disease, Tbilisi, Georgia.
Charles A PeloquinUniversity of Florida, College of Pharmacy, Gainesville, FL, USA.

Funding

Implementing a Maternal health and PRegnancy Outcomes Vision for Everyone (IMPROVE)UL1TR002378 · NCATS · EMORY UNIVERSITY · PI Andres J Garcia, Elizabeth O. Ofili · 2017 to 2026
$92.1M
Atlanta Clinical and Translational Science Institute (ACTSI) RenewalUL1TR000454 · NCATS · EMORY UNIVERSITY · PI STEPHENS, DAVID S · 2012 to 2016
$25.8M
Emory-Georgia TB Research Training ProgramD43TW007124 · FIC · EMORY UNIVERSITY · PI HENRY M BLUMBERG, Nestani Tukvadze · 2004 to 2026
$4.6M
Intra Cavitary Pharmacokinetics and Drug Resistance in Pulmonary TuberculosisK23AI103044 · NIAID · EMORY UNIVERSITY · PI KEMPKER, RUSSELL RYAN · 2013 to 2017
$910k
A Clinical Pharmacology Study of a Novel Drug Regimen for Pre XDR and XDR TuberculosisR21AI122001 · NIAID · EMORY UNIVERSITY · PI KEMPKER, RUSSELL RYAN · 2016 to 2017
$369k
FIC NIH HHS D43 TW007124NCATS NIH HHS UL1 TR000454NCATS NIH HHS UL1 TR002378NIAID NIH HHS K23 AI103044NIAID NIH HHS R21 AI122001
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AdultAntitubercular AgentsExtensively Drug-Resistant TuberculosisHumansLinezolidMaleMycobacterium tuberculosisTuberculosis, Multidrug-ResistantAntitubercular AgentsLinezolid

Identifiers

PMID29437945
PMCPMC6223612

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.