Evidence map›Paper›PMID 29437921›Full record

ArticlemBio2018

Expanding Primary Metabolism Helps Generate the Metabolic Robustness To Facilitate Antibiotic Biosynthesis in

Jana K Schniete, Pablo Cruz-Morales, Nelly Selem-Mojica, Lorena T Fernández-Martínez, Iain S Hunter, Francisco Barona-Gómez, Paul A Hoskisson

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
5.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 55 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Comparative genome analysis and secondary biosynthetic potential of the Streptomyces microflavus strains isolated from high altitude.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2026
    Article
  5. Article
  6. Transcriptional analysis of genes associated with glycolysis in Streptomyces coelicolor M145.International microbiology : the official journal of the Spanish Society for Microbiology · 2025
    Article
  7. Application of multiple genomic-editing technologies inSynthetic and systems biotechnology · 2025
    Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. A roadmap for metagenomic enzyme discovery.Natural product reports · 2021
    Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jana K SchnieteStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.ORCID 0000-0003-4274-5839
Pablo Cruz-MoralesEvolution of Metabolic Diversity Laboratory, Langebio, Guanajuato, Mexico.
Nelly Selem-MojicaEvolution of Metabolic Diversity Laboratory, Langebio, Guanajuato, Mexico.
Lorena T Fernández-MartínezDepartment of Biology, Edge Hill University, Ormskirk, Lancashire, United Kingdom.
Iain S HunterStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom.
Francisco Barona-GómezEvolution of Metabolic Diversity Laboratory, Langebio, Guanajuato, Mexico.
Paul A HoskissonStrathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, United Kingdom Paul.hoskisson@strath.ac.uk.ORCID 0000-0003-4332-1640
University of Strathclyde · GBEdge Hill University · GB

Funding

Biotechnology and Biological Sciences Research Council
6 · The paper itself

Abstract

The expansion of the genetic repertoire of an organism by gene duplication or horizontal gene transfer (HGT) can aid adaptation.

Indexed as

Anti-Bacterial AgentsGene DuplicationGene ExpressionKineticsMetabolic Networks and PathwaysMultigene FamilyPyruvate KinaseStreptomyces coelicolorAnti-Bacterial AgentsPyruvate Kinaseactinobacteriaantibioticsevolutionprimary metabolismpyruvate kinaseStreptomyces

Identifiers

PMID29437921
PMCPMC5801464
OpenAlexW2789002707

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.