Evidence map›Paper›PMID 29437850›Full record

ArticleJournal of bacteriology2018

Targeting the HUβ Protein Prevents Porphyromonas gingivalis from Entering into Preexisting Biofilms.

Christopher J Rocco, Lauren O Bakaletz, Steven D Goodman

Open access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Secretome analysis and virulence assessment inJournal of oral microbiology · 2024
    Article
  4. Review
  5. Antimicrobial resistance and mechanisms of epigenetic regulation.Frontiers in cellular and infection microbiology · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Characterization of the nasopharynx microbiota in patients with nasopharyngeal carcinoma vs. healthy controls.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2021
    Article
  12. Article
  13. The dental plaque biofilm matrix.Periodontology 2000 · 2021
    Review
  14. Article
  15. Review
  16. Article
  17. Review
  18. The Role of Exopolysaccharides in Oral Biofilms.Journal of dental research · 2019
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Christopher J RoccoCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Lauren O BakaletzCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA.
Steven D GoodmanCenter for Microbial Pathogenesis, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio, USA Steven.Goodman@NationwideChildrens.org.
Nationwide Children's Hospital · US

Funding

Novel immunotherapeutics for the management of otitis media due to H. influenzaeR01DC011818 · NIDCD · RESEARCH INST NATIONWIDE CHILDREN'S HOSP · PI BAKALETZ, LAUREN O, GOODMAN, STEVEN D · 2011 to 2020
$5.4M
NIDCD NIH HHS R01 DC011818
6 · The paper itself

Abstract

The oral cavity is home to a wide variety of bacterial species, both commensal, such as various streptococcal species, and pathogenic, such as

Indexed as

Amino Acid SequenceBacterial ProteinsBacteroidaceae InfectionsBiofilmsDNA-Binding ProteinsHumansMouthPeriodontitisPorphyromonas gingivalisSequence AlignmentBacterial ProteinsDNA-Binding Proteinshistone-like protein HU, bacteriaantibodybiofilmDNABIIPorphyromonas gingivalisstreptococci

Identifiers

PMID29437850
PMCPMC5952391
OpenAlexW2789716727

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.