Evidence map›Paper›PMID 29437757›Full record

ArticleBMJ open2018

Sexual inequality in incident tuberculosis: a cohort study in Taiwan.

Yung-Feng Yen, Hsiao-Yun Hu, Ya-Ling Lee, Po-Wen Ku, Ming-Chung Ko, Pei-Hung Chuang, Yun-Ju Lai, Dachen Chu

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Yung-Feng YenSection of Infectious Diseases, Taipei City Hospital, Taipei, Taiwan.
Hsiao-Yun HuInstitute of Public Health and Community Medicine Research Center, National Yang-Ming University, Taipei, Taiwan.
Ya-Ling LeeDepartment of Dentistry, Taipei City Hospital, Taipei, Taiwan.
Po-Wen KuGraduate Institute of Sports and Health, National Changhua University of Education, Changhua, Taiwan.
Ming-Chung KoDepartment of Health Care Management, National Taipei University of Nursing and Health Sciences, Taipei, Taiwan.
Pei-Hung ChuangCenter for Prevention and Treatment of Occupational Injury and Diseases, Taipei Veterans General Hospital, Taipei, Taiwan.
Yun-Ju Lai *School of Medicine, National Yang-Ming University, Taipei, Taiwan.
Dachen Chu *School of Medicine, National Yang-Ming University, Taipei, Taiwan.
National Taipei University of Nursing and Health Science · TWNational Yang Ming Chiao Tung University · TWMinistry of Health and Welfare · TWNational Changhua University of Education · TWNational Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveAnimal studies showed that male subjects had lower activity of immune response to infections than female subjects, which may increase the risk of the development of tuberculosis in male population. This study intended to investigate the risk of incident tuberculosis in male and female adults in Taiwan.

designThis is a retrospective cohort study.

settingThe present analyses used data of Taiwan National Health Interview Survey 2001, 2005 and 2009, National Register of Deaths Dataset, and National Health Insurance Research Database from 2000 to 2013.

participantsA total of 43 424 subjects with a mean age of 43.04 years were analysed. PRIMARY OUTCOME MEASURES: Incidence of tuberculosis.

resultsDuring 381 561 person-years of follow-up period, incident tuberculosis was recognised in 268 individuals. The incidence rates of tuberculosis were 97.56 and 43.24 per 100 000 person-years among male and female participants, respectively. Kaplan-Meier curves comparing male and female subjects showed statistical significance (log-rank test, P value<0.01). After adjusting for subjects' demographics and comorbidities, men showed increased risks of incident tuberculosis (adjusted HR, 1.68; 95% CI 1.21 to 2.34; P value<0.01) compared with women. On subgroup analysis, after stratifying by age, smoking and alcohol use, men had a higher risk of incident tuberculosis than women in all patient subgroups, except those who were current smokers.

conclusionsThis study suggests that men had a higher risk of incident tuberculosis than women. Future tuberculosis control programmes should particularly target the male population.

Indexed as

Sex DistributionAdultComorbidityFemaleHumansIncidenceKaplan-Meier EstimateMaleMiddle AgedMultivariate AnalysisProportional Hazards ModelsRetrospective StudiesRisk FactorsSmokingTaiwanTuberculosiscohort studysextuberculosis

Identifiers

PMID29437757
PMCPMC5829922
OpenAlexW2791968521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.