Evidence map›Paper›PMID 29437726›Full record

ArticleGenes & development2018

Protein synthesis controls phosphate homeostasis.

Mauricio H Pontes, Eduardo A Groisman

Open access · diamondAbstract read
In one paragraph

Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 58 citations in OpenAlex.

  1. Microbiology spectrum · 2026
    Article
  2. Polyphosphate synthesis is essential for phosphate and ATP homeostasis during nutrient upshift.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Analysis of stress-induced small proteins inbioRxiv : the preprint server for biology · 2025
    Article
  8. Article
  9. Cytoplasmic MgProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Article
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  13. Article
  14. Article
  15. bioRxiv : the preprint server for biology · 2024
    Article
  16. Review
  17. Article
  18. How Bacterial Pathogens Coordinate Appetite with Virulence.Microbiology and molecular biology reviews : MMBR · 2023
    Review
  19. Article
  20. Frequency and Risk Factors of Hypophosphatemia in Patients Admitted to Emergency Intensive Care Unit in Zagazig University Hospitals.Indian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Mauricio H PontesDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut 06536, USA.
Eduardo A GroismanDepartment of Microbial Pathogenesis, Yale School of Medicine, New Haven, Connecticut 06536, USA.
Yale University · US

Funding

REGULATION OF SALMONELLA VIRULENCE BY THE PHOP PROTEINR01AI049561 · NIAID · YALE UNIVERSITY · PI Eduardo Groisman · 2001 to 2026
$9.7M
NIAID NIH HHS R01 AI049561
6 · The paper itself

Abstract

Phosphorus is an essential element assimilated largely as orthophosphate (Pi). Cells respond to Pi starvation by importing Pi from their surroundings. We now report that impaired protein synthesis alone triggers a Pi starvation response even when Pi is plentiful in the extracellular milieu. In the bacterium

Indexed as

Protein BiosynthesisAdenosine TriphosphatasesBacterial ProteinsCation Transport ProteinsEscherichia coliHomeostasisMagnesiumMembrane Transport ProteinsPhosphatesProtein Synthesis InhibitorsSaccharomyces cerevisiaeSalmonella typhimuriumTranscription, GeneticAdenosine TriphosphatasesBacterial ProteinsCation Transport ProteinsMagnesiumMembrane Transport ProteinsMgtA protein, bacteriaMgtB protein, Salmonella typhimuriumMgtC protein, Salmonella typhimuriumPhoB protein, BacteriaPhosphatesProtein Synthesis InhibitorsATPMg2+PhoB/PhoRPhoP/PhoQPitranslation

Identifiers

PMID29437726
PMCPMC5828397
OpenAlexW2786960368

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.