ArticleBMJ case reports2018
Symmetrical peripheral gangrene of bilateral feet and unilateral hand after administration of vasopressors during septic shock.
Article in BMJ case reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 29 citations in OpenAlex.
- Life-saving but limb-threatening: vasopressor-induced acral ischaemia and necrosis - two cases and review of the literature.Archives of medical sciences. Atherosclerotic diseases · 2026Article
- Symmetrical peripheral gangrene after cardiac surgery: A case report and review of literature.Medicine · 2025Review
- Relationship Between Symmetrical Peripheral Gangrene Patients and Using Vasopressors in the Intensive Care Unit.Cureus · 2024Review
- An Uncommon Presentation of Vasopressin-Induced Purpura Fulminans.Journal of medical cases · 2023Article
- Acute Upper Limb Ischemia and Amputation Post Antecubital Fossa Cannulation: A Report of Two Postpartum Patients.Cureus · 2023Article
- Novel Classification of Thrombotic Disorders Based on Molecular Hemostasis and Thrombogenesis Producing Primary and Secondary Phenotypes of Thrombosis.Biomedicines · 2022Review
- Review
- The Epidemiology of Extremity Threat and Amputation after Vasopressor-Dependent Sepsis.Annals of the American Thoracic Society · 2022Article
- Symmetrical Peripheral Gangrene: Report of Three Cases.Case reports in critical care · 2022Article
- The effect of topical nitroglycerin on symmetrical peripheral gangrene in a pediatric patient.Clinical case reports · 2021Article
- Article
- Dermatological Manifestations in the Intensive Care Unit: A Practical Approach.Critical care research and practice · 2020Review
- Symmetrical Peripheral Gangrene Associated with Low Output Cardiac Failure.Medicina (Kaunas, Lithuania) · 2019Article
- Sepsis and septic shock: endothelial molecular pathogenesis associated with vascular microthrombotic disease.Thrombosis journal · 2019Review
- Symmetrical Peripheral Gangrene: A Rare Complication of Severe Illness.Indian dermatology online journalArticle
- NovoSorb® Biodegradable Temporising Matrix (BTM) for reconstruction of paediatric acute ischaemic limb injuries secondary to sepsis: A literature review and case series.Scars, burns & healingArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We report a case of a 75-year-old Hispanic man treated for septic shock after undergoing surgery for impacted renal stones. He was given vasopressors and later developed symmetrical peripheral gangrene (SPG) on both his feet and left hand. SPG is a serious and rare condition presenting clinically as an acute onset of ischaemia with no vessel occlusion. Vasopressors are identified as a contributing factor in SPG development. The patient ultimately underwent transmetatarsal amputations of both feet and amputation of three digits on his left hand. Early monitoring and swift management of peripheral ischaemia are essential when using vasopressors for the treatment of septic shock.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.