Evidence map›Paper›PMID 29437624›Full record

ArticleAntimicrobial agents and chemotherapy2018

Posaconazole MIC Distributions for Aspergillus fumigatus Species Complex by Four Methods: Impact of

A Espinel-Ingroff, J Turnidge, A Alastruey-Izquierdo, E Dannaoui, G Garcia-Effron, J Guinea, S Kidd, T Pelaez, M Sanguinetti, J Meletiadis and 17 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  15. Exploration of Clinical Breakpoint of Danofloxacin forAntibiotics (Basel, Switzerland) · 2021
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  16. Article
  17. A Novel Combination ofAntimicrobial agents and chemotherapy · 2020
    Article
  18. Review
  19. Epidemiology and Antifungal Susceptibility Profile ofJournal of clinical microbiology · 2019
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors at 20 institutions in 16 countries.

A Espinel-IngroffVCU Medical Center, Richmond, Virginia, USA victoria.ingroff@vcuhealth.org.
J TurnidgeUniversity of Adelaide, Adelaide, Australia.
A Alastruey-IzquierdoMycology Reference Laboratory, National Centre for Microbiology, Instituto de Salud Carlos III, Majadahonda, Madrid, Spain.ORCID 0000-0001-8651-4405
E DannaouiUniversité Paris-Descartes, Faculté de Médecine, APHP, Hôpital Européen Georges Pompidou, Unité de Parasitologie-Mycologie, Service de Microbiologie, Paris, France.ORCID 0000-0002-2817-3830
G Garcia-EffronLaboratorio de Micología y Diagnóstico Molecular-Facultad de Bioquímica y Ciencias Biológicas-Universidad Nacional del Litoral, Consejo Nacional de Investigaciones Científicas y Tecnológicas (CONICET), CCT, Santa Fe, Argentina.
J GuineaServicio de Microbiología Clínica y Enfermedades Infecciosas-VIH, Hospital General Universitario Gregorio Marañon, and Instituto de Investigación Sanitaria Gregorio Marañón, Madrid, Spain.ORCID 0000-0002-7901-8355
S KiddNational Mycology Reference Centre, Microbiology & Infectious Diseases, SA Pathology, Adelaide, Australia.
T PelaezServicio de Microbiología, Hospital Universitario Central de Asturias, Asturias, Spain.
M SanguinettiInstitute of Microbiology, Università Cattolica del Sacro Cuore, Rome, Italy.
J MeletiadisClinical Microbiology Laboratory, Attikon Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
F BotterelUnité de Parasitologie-Mycologie, Département de Virologie, Bactériologie-Hygiène, Parasitologie-Mycologie, DHU VIC, CHU Henri Mondor, Créteil, France.
B BustamanteInstituto de Medicina Tropical Alexander von Humboldt-Universidad Peruana Cayetano Heredia, Lima, Peru.
Y-C ChenDepartment of Internal Medicine, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan.
A ChakrabartiDepartment of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
A ChowdharyDepartment of Medical Mycology, Vallabhbhai Patel Chest Institute, University of Delhi, Delhi, India.
E ChryssanthouKlinisk Mikrobiologi, Karolinska, Universitetlaboratoriet, Karolinska, Universitetssjukhuset, Stockholm, Sweden.
S CórdobaInstituto Nacional de Enfermedades Infecciosas Dr. C. G. Malbrán, Buenos Aires, Argentina.
G M GonzalezUniversidad Autonóma de Nuevo León, Monterrey, Nuevo León, México.
J GuarroMycology Unit Medical School, Universitat Rovira i Virgili, Reus, Spain.
E M JohnsonMycology Reference Laboratory, Public Health England, Bristol, United Kingdom.
J V KusPublic Health Ontario, Toronto, Ontario, Canada.
C Lass-FlörlNational Mycology Reference Centre, Division of Hygiene and Medical Microbiology, Medical University of Innsbruck, Innsbruck, Austria.
M J Linares-SiciliaUniversidad de Córdoba, H. G. U. Reina Sofía, Córdoba, Spain.
E Martín-MazuelosUnidad de Gestión Clínica de Enfermedades Infecciosas y Microbiología, Hospital de Valme, Seville, Spain.
C E NegriUniversidade Federal de São Paulo, Laboratório Especial de Micologia, São Paulo, Brazil.
M A PfallerUniversity of Iowa College of Medicine, Iowa City, Iowa, USA.
A M TortoranoDepartment of Biomedical Sciences for Health, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0003-2093-8250
Administración Nacional de Laboratorios e Institutos de Salud · ARCentre Hospitalier Universitaire Henri-Mondor · FRConsejo Nacional de Investigaciones Científicas y Técnicas · ARHospital General Universitario Gregorio Marañón · ESHospital Universitario Central de Asturias · ESHospital Universitario de Valme · ESInnsbruck Medical University · ATInstituto de Salud Carlos III · ESKarolinska University Hospital · SENational and Kapodistrian University of Athens · GRNational Taiwan University Hospital · TWPost Graduate Institute of Medical Education and Research · INPublic Health England · GBPublic Health Ontario · CASouth Australia Pathology · AUThe University of Adelaide · AUUniversidad Autónoma de Nuevo León · MXUniversidade Federal de São Paulo · BRUniversidad Peruana Cayetano Heredia · PEUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Estimating epidemiological cutoff endpoints (ECVs/ECOFFS) may be hindered by the overlap of MICs for mutant and nonmutant strains (strains harboring or not harboring mutations, respectively). Posaconazole MIC distributions for the

Indexed as

Antifungal AgentsAspergillus fumigatusDrug Resistance, FungalMicrobial Sensitivity TestsMutationTriazolesVoriconazoleAntifungal AgentsposaconazoleTriazolesVoriconazoleAspergillus fumigatusCLSI ECVscyp51A mutantsECVsEtestEUCAST ECVsposaconazoleSYOtriazole resistancewild type

Identifiers

PMID29437624
PMCPMC5913929
OpenAlexW2791396313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.