Evidence map›Paper›PMID 29437601›Full record

ArticleJournal of the American Heart Association2018

Relationship Between the Ambulatory Arterial Stiffness Index and the Lower Limit of Cerebral Autoregulation During Cardiac Surgery.

Yurie Obata, Viachaslau Barodka, Dan E Berkowitz, Allan Gottschalk, Charles W Hogue, Jochen Steppan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of the American Heart Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Pulse pressure and perioperative stroke.Current opinion in anaesthesiology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Yurie ObataDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Viachaslau BarodkaDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Dan E BerkowitzDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Allan GottschalkDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD.
Charles W HogueDepartment of Anesthesiology, Northwestern University Feinberg, Chicago, IL.
Jochen SteppanDepartment of Anesthesiology and Critical Care Medicine, Johns Hopkins University, Baltimore, MD J.Steppan@jhmi.edu.

Funding

Continuous Cerebral Autoregulation Monitoring to Reduce Brain Injury from CardiacR01HL092259 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI HOGUE, CHARLES W · 2009 to 2018
$3.4M
NHLBI NIH HHS R01 HL092259
6 · The paper itself

Abstract

backgroundPulse pressure, the ambulatory arterial stiffness index (AASI), and the symmetric AASI are established predictors of adverse cardiovascular outcomes. However, little is known about their relationship to cerebral autoregulation. This study evaluated whether these markers of vascular properties relate to the lower limit of cerebral autoregulation (LLA). METHODS AND

resultsThe LLA was determined during cardiac surgery with transcranial Doppler ultrasonography in 181 patients. All other variables were calculated from continuous intraoperative readings obtained before cardiopulmonary bypass. The LLA varied directly with the AASI (β=3.12 per 0.1 change in AASI,

conclusionsThese data indicate that the LLA is related to the mechanical properties of the vasculature as represented by the AASI. The AASI can be used to predict LLA threshold levels during cardiac surgery. It is now possible to link elevations in the LLA with an increased AASI as determined from readily accessible intraoperative variables.

Indexed as

Cardiac Surgical ProceduresCerebrovascular CirculationVascular StiffnessAgedAged, 80 and overCerebral ArteriesFemaleHomeostasisHumansIntraoperative PeriodMaleMiddle AgedRetrospective StudiesTime FactorsUltrasonography, Doppler, Transcranialambulatory arterial stiffness indexcardiac surgerycerebral autoregulationlower limit of cerebral autoregulationpulse pressure

Identifiers

PMID29437601
PMCPMC5850197

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.