Trial reportThe Journal of asthma : official journal of the Association for the Care of Asthma2019
Controller adherence following hospital discharge in high risk children: A pilot randomized trial of text message reminders.
Trial report in The Journal of asthma : official journal of the Association for the Care of Asthma, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Systematic review and meta-analysis of interventions to promote medication adherence among children, adolescents, and young adults with medical conditions.Journal of pediatric psychology · 2025Pooled it
- Understanding the effectiveness and design of parent-oriented mobile health interventions: a systematic review and narrative synthesis.BMC pediatrics · 2025Pooled it
- Digital interventions to improve adherence to maintenance medication in asthma.The Cochrane database of systematic reviews · 2022Pooled it
- Features of successful interventions to improve adherence to inhaled corticosteroids in children with asthma: A narrative systematic review.Pediatric pulmonology · 2022Pooled it
- Meta-Analysis of Adherence Promotion Interventions in Pediatric Asthma.Journal of pediatric psychology · 2021Pooled it
- Single maintenance and reliever therapy strategies for Implementation and effectiveness trial (SMART & SIMPLE Trial): study protocol for a type II hybrid effectiveness-implementation cluster-randomized controlled trial.Contemporary clinical trials communications · 2026Article
- A Comprehensive Scoping Review of Technology in the Care of Historically Marginalized Populations With Asthma: A Work Group Report of the AAAAI Diversity, Equity, and Inclusion Committee.The journal of allergy and clinical immunology. In practice · 2025Article
- Participant Perspectives on the Implementation of a School-Linked Text-Message Intervention to Improve Pediatric Asthma Medication Adherence.Pediatric allergy, immunology, and pulmonology · 2024Article
- The Use of eHealth for Pharmacotherapy Management With Patients With Respiratory Disease, Cardiovascular Disease, or Diabetes: Scoping Review.Journal of medical Internet research · 2023Article
- Trajectories of Controller Therapy Use Before and After Asthma-Related Hospitalization in Children and Adults: Population-Based Retrospective Cohort Study.JMIR public health and surveillance · 2023Article
- eHealth Technologies for Monitoring Pediatric Asthma at Home: Scoping Review.Journal of medical Internet research · 2023Article
- Optimizing intervention components for sleep promotion in children in the context of obesity prevention: the SLEEPY 2.0 study protocol.Frontiers in sleep · 2023Article
- Article
- Adherence and Self-management Interventions among Systemically Marginalized and Underserved Youth with Asthma.Clinical practice in pediatric psychology · 2022Article
- A response to COVID-19 school closures: The feasibility of a school-linked text message intervention as an adaptation to school-supervised asthma therapy.Pediatric pulmonology · 2022Article
- Digital Inhalers for Asthma or Chronic Obstructive Pulmonary Disease: A Scientific Perspective.Pulmonary therapy · 2021Review
- Design, methods, and baseline characteristics of a pilot, randomized, controlled trial of the effects of an electronic monitoring device on medication adherence in children with asthma.Contemporary clinical trials communications · 2021Article
- An Asthma Population Health Improvement Initiative for Children With Frequent Hospitalizations.Pediatrics · 2020Article
- They just don't take their medicines: Reframing medication adherence in asthma from frustration to opportunity.Pediatric pulmonology · 2020Review
- Aerosol Therapy in Asthma-Why We Are Failing Our Patients and How We Can Do Better.Frontiers in pediatrics · 2020Review
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
objectiveTo assess the feasibility of a mobile health, inhaled corticosteroid (ICS) adherence reminder intervention and to characterize adherence trajectories immediately following severe asthma exacerbation in high-risk urban children with persistent asthma.
methodsChildren aged 2-13 with persistent asthma were enrolled in this pilot randomized controlled trial during an asthma emergency department (ED) visit or hospitalization. Intervention arm participants received daily text message reminders for 30 days, and both arms received electronic sensors to measure ICS use. Primary outcomes were feasibility of sensor use and text message acceptability. Secondary outcomes included adherence to prescribed ICS regimen and 30-day adherence trajectories. Group-based trajectory modeling was used to examine adherence trajectories.
resultsForty-one participants (mean age 5.9) were randomized to intervention (n = 21) or control (n = 20). Overall, 85% were Black, 88% had public insurance, and 51% of the caregivers had a high school education or less. Thirty-two participant families (78%) transmitted medication adherence data; of caregivers who completed the acceptability survey, 25 (96%) chose to receive daily reminders beyond that study interval. Secondary outcome analyses demonstrated similar average daily adherence between groups (intervention = 36%; control = 32%, P = 0.73). Three adherence trajectories were identified with none ever exceeding 80% adherence.
conclusionsWithin a high-risk pediatric cohort, electronic monitoring of ICS use and adherence reminders delivered via text message were feasible for most participants, but there was no signal of effect. Adherence trajectories following severe exacerbation were suboptimal, demonstrating an important opportunity for asthma care improvement.
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