Evidence map›Paper›PMID 29437272›Full record

ArticleJournal of biomedical materials research. Part B, Applied biomaterials2018

Bioactivity and composition of a preserved connective tissue matrix derived from human placental tissue.

Joseph Irvin, Carina Danchik, Joseph Rall, Annie Babcock, Matthew Pine, Devin Barnaby, Joseph Pathakamuri, Daniel Kuebler

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of biomedical materials research. Part B, Applied biomaterials, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05297513 (Efficacy of ActiveMatrix on Spinal Surgical Site Infection), which is not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05297513 phase4unknown statusnot on this mapstarted 2022, after this paper: background citation

Efficacy of ActiveMatrix on Spinal Surgical Site Infection (SSI) Reduction: A Single-blinded Randomized Controlled Trial

TypeinterventionalSponsorBaylor College of MedicineRan2022 to 2026Enrolled275ConditionsSpinal Stenosis Lumbar, Surgical Site Infection, Back Pain Lower Back ChronicArmsActiveMatrix
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Amniotic growth factors enhanced human pre-adipocyte cell viability and differentiation under hypoxia.Journal of biomedical materials research. Part B, Applied biomaterials · 2022
    Article
  5. Article
  6. Review
  7. Bioactivity and composition of a preserved connective tissue matrix derived from human placental tissue.Journal of biomedical materials research. Part B, Applied biomaterials · 2018
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joseph IrvinDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Carina DanchikDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Joseph RallDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Annie BabcockDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Matthew PineDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Devin BarnabyDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Joseph PathakamuriDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.
Daniel KueblerDepartment of Biology, Franciscan University of Steubenville, Steubenville, Ohio, 43952.ORCID 0000-0001-8641-8149
Franciscan University of Steubenville · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are a wide variety of extracellular matrices that can be used for regenerative purposes. Placental tissue-based matrices are quickly becoming an attractive option given the availability of the tissue source and the wide variety of bioactive molecules knows to exist in unprocessed placental tissues. As fresh placental tissues are seldom an option at the point of care, we examined both the composition and bioactivity of a commercially packaged flowable placental connective tissue matrix (FPTM) (BioECM

Indexed as

Cell ProliferationPreservation, BiologicalAdipose TissueCell Culture TechniquesExtracellular MatrixFemaleHumansIntercellular Signaling Peptides and ProteinsPlacentaPregnancyStaphylococcus aureusStaphylococcus saprophyticusStem CellsIntercellular Signaling Peptides and Proteinsadipose-derived stromal/stem cellsconnective tissueextracellular matrixgrowth factorsplacenta

Identifiers

PMID29437272
PMCPMC6220977
OpenAlexW2789445153

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.