Evidence map›Paper›PMID 29437043›Full record

ArticleBiology open2018

The histone deacetylase HDAC1 positively regulates Notch signaling during

Zehua Wang, Jialan Lyu, Fang Wang, Chen Miao, Zi Nan, Jiayu Zhang, Yongmei Xi, Qi Zhou, Xiaohang Yang, Wanzhong Ge

Open access · goldAbstract read
In one paragraph

Article in Biology open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Impaired Blastocyst Formation inInternational journal of molecular sciences · 2023
    Article
  8. Article
  9. Article
  10. Deletion of a putative HDA-1 binding site in themicroPublication biology · 2021
    Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Zehua WangDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Jialan LyuDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.ORCID http://orcid.org/0000-0003-1036-4134
Fang WangCollege of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Chen MiaoDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Zi NanCollege of Life Sciences, Zhejiang University, Hangzhou, Zhejiang 310058, China.ORCID http://orcid.org/0000-0001-5056-7708
Jiayu ZhangLife Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Yongmei XiDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Qi ZhouLife Sciences Institute, Zhejiang University, Hangzhou, Zhejiang 310058, China.
Xiaohang YangDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China.
Wanzhong GeDivision of Human Reproduction and Developmental Genetics, The Women's Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310058, China wanzhongge@zju.edu.cn.ORCID http://orcid.org/0000-0003-1334-2723
Women's Hospital, School of Medicine, Zhejiang University · CNZhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Notch signaling pathway is highly conserved across different animal species and plays crucial roles in development and physiology. Regulation of Notch signaling occurs at multiple levels in different tissues and cell types. Here, we show that the histone deacetylase HDAC1 acts as a positive regulator of Notch signaling during

Indexed as

AtrophinDrosophila wing developmentHDAC1Notch

Identifiers

PMID29437043
PMCPMC5861358
OpenAlexW2789483055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.