← PCSK9 inhibitors × lipids

TrialDiabetes, obesity & metabolism2018

Alirocumab vs usual lipid-lowering care as add-on to statin therapy in individuals with type 2 diabetes and mixed dyslipidaemia: The ODYSSEY DM-DYSLIPIDEMIA randomized trial.

Kausik K Ray et al.PubMed ↗Full text ↗Publisher ↗

The primary results report of NCT02642159. Its numbers are set against the trial’s posted results below.

What the trial testedas reported · 821 people · 2018

No range given

Reported lower lipids, no range given

−27.0

As reported

difference −27.0, no interval

Against the trial’s posted results

  • Read here as one end of the posted intervalThis paper difference −27.0Posted, primary outcome difference −32.5 (−38.1 to −27.0), p <0.0001Percent Change From Baseline in Non-HDL-C at Week 24: Overall Intent-to-treat (ITT) AnalysisThe number read from the abstract is an end of the interval, not the estimate, so it does not vote.

One number in the abstract

the abstract, start to end

… UC, 97.5% confidence interval -38.1 to -27.0; P < .0001).

← favours treatmentfavours comparator →
could be chance
No interval given · direction only, strength unknown
Lipids
−27.0
PCSK9 inhibitorsLipids
1 / 3

47 papers cite it

2018
2019
2020
2021
2022
2023
2024
2025
2026
this paperpooled ittrialcites it

The trial

Full record →Abstract, authors, funding and every citing paper · PMID 29436756