Evidence map›Paper›PMID 29436510›Full record

ArticleJournal of the Royal Society, Interface2018

Hidden Markov models for monitoring circadian rhythmicity in telemetric activity data.

Qi Huang, Dwayne Cohen, Sandra Komarzynski, Xiao-Mei Li, Pasquale Innominato, Francis Lévi, Bärbel Finkenstädt

Abstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Trial
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  6. Observational
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  14. Artificial intelligence and machine learning in precision and genomic medicine.Medical oncology (Northwood, London, England) · 2022
    Review
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qi HuangDepartment of Statistics, University of Warwick, Coventry, CV4 7AL, UK.ORCID 0000-0003-4456-2999
Dwayne CohenDepartment of Statistics, University of Warwick, Coventry, CV4 7AL, UK.
Sandra KomarzynskiMedical School, University of Warwick, Coventry, CV4 7AL, UK.ORCID 0000-0003-3886-6494
Xiao-Mei LiINSERM U935, Hospital Paul Brousse and University Paris-Saclay, Villejuif, 94800, France.ORCID 0000-0002-1096-2495
Pasquale InnominatoMedical School, University of Warwick, Coventry, CV4 7AL, UK.ORCID 0000-0002-0653-8261
Francis LéviMedical School, University of Warwick, Coventry, CV4 7AL, UK.ORCID 0000-0003-1364-7463
Bärbel FinkenstädtDepartment of Statistics, University of Warwick, Coventry, CV4 7AL, UK b.f.finkenstadt@warwick.ac.uk.ORCID 0000-0001-7754-1380

Funding

Medical Research Council MR/M013170/1
6 · The paper itself

Abstract

Wearable computing devices allow collection of densely sampled real-time information on movement enabling researchers and medical experts to obtain objective and non-obtrusive records of actual activity of a subject in the real world over many days. Our interest here is motivated by the use of activity data for evaluating and monitoring the circadian rhythmicity of subjects for research in chronobiology and chronotherapeutic healthcare. In order to translate the information from such high-volume data arising we propose the use of a Markov modelling approach which (i) naturally captures the notable square wave form observed in activity data along with heterogeneous ultradian variances over the circadian cycle of human activity, (ii) thresholds activity into different states in a probabilistic way while respecting time dependence and (iii) gives rise to circadian rhythm parameter estimates, based on probabilities of transitions between rest and activity, that are interpretable and of interest to circadian research.

Indexed as

Circadian RhythmModels, TheoreticalTelemetryWearable Electronic DevicesFemaleHumansMaleMarkov Chainsaccelerometer dataactivity countscircadian rhythm in rest–activityhidden Markov models

Identifiers

PMID29436510
PMCPMC5832732

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.