Evidence map›Paper›PMID 29436413›Full record

ArticleJournal of immunology (Baltimore, Md. : 1950)2018

Many Th Cell Subsets Have Fas Ligand-Dependent Cytotoxic Potential.

Dmitri I Kotov, Jessica A Kotov, Michael F Goldberg, Marc K Jenkins

Open access · bronzeAbstract read
In one paragraph

Article in Journal of immunology (Baltimore, Md. : 1950), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 27 citations in OpenAlex.

  1. Cytotoxic CD4Signal transduction and targeted therapy · 2026
    Review
  2. Article
  3. Article
  4. FAS mediates apoptosis, inflammation, and treatment of pathogen infection.Frontiers in cellular and infection microbiology · 2025
    Review
  5. Review
  6. Review
  7. Article
  8. Cytotoxic CD4eLife · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Innate and Adaptive Immune Responses duringMicrobiology spectrum · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Dmitri I KotovDepartment of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455.ORCID 0000-0001-7843-1503
Jessica A KotovDepartment of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455.
Michael F GoldbergDepartment of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455.
Marc K JenkinsDepartment of Microbiology and Immunology, Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455 jenki002@umn.edu.ORCID 0000-0001-8009-7655
University of Minnesota Medical Center · US

Funding

Type I interferons in tolerance in the steady stateP01AI035296 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI HOGQUIST, KRISTIN A. · 1993 to 2023
$31.1M
TRAINING IN HEMOGLOBIN &CELL MEMBRANE RESEARCHT32HL007062 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller, Gregory M Vercellotti · 1985 to 2026
$10.3M
TRACKING CD4+ MEMORY T CELLS IN VIVOR01AI039614 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JENKINS, MARC KEVIN · 1996 to 2023
$8.7M
IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
COSTIMULATORY SIGNALS IN CD4+ T-CELL ACTIVATIONR01AI027998 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI JENKINS, MARC KEVIN · 1989 to 2022
$4.5M
Protective CD4+ T CellsR01AI103760 · NIAID · UNIVERSITY OF MINNESOTA · PI JENKINS, MARC KEVIN · 2013 to 2022
$4.2M
Costimulatory Signals in CD4+ T Cell ActivationR37AI027998 · NIAID · UNIVERSITY OF MINNESOTA · PI JENKINS, MARC KEVIN · 2008 to 2017
$3.7M
Minnesota Training Program in VirologyT32AI083196 · NIAID · UNIVERSITY OF MINNESOTA · PI Louis M Mansky · 2010 to 2026
$3.2M
NHLBI NIH HHS T32 HL007062NIAID NIH HHS P01 AI035296NIAID NIH HHS R01 AI027998NIAID NIH HHS R01 AI039614NIAID NIH HHS R01 AI103760NIAID NIH HHS R37 AI027998NIAID NIH HHS T32 AI007313NIAID NIH HHS T32 AI083196
6 · The paper itself

Abstract

CD4

Indexed as

AnimalsCD4-Positive T-LymphocytesFas Ligand Proteinfas ReceptorLymphocyte ActivationMiceMice, Inbred C57BLTh17 CellsTh1 CellsT-Lymphocytes, CytotoxicFas Ligand ProteinFas protein, mousefas Receptor

Identifiers

PMID29436413
PMCPMC5840022
OpenAlexW2785865202

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.