ArticleDiabetes care2018
Increasing Mortality in Adults With Diabetes and Low Estimated Glomerular Filtration Rate in the Absence of Albuminuria.
Article in Diabetes care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Efficacy of traditional Chinese medicine injection for diabetic kidney disease: A network meta analysis and systematic review.Frontiers in pharmacology · 2023Pooled it
- Protective effect of paeoniflorin in diabetic nephropathy: A preclinical systematic review revealing the mechanism of action.PloS one · 2023Pooled it
- Pooled it
- Chinese herbal medicine for diabetic kidney disease: a systematic review and meta-analysis of randomised placebo-controlled trials.BMJ open · 2019Pooled it
- Dickkopf-3 (DKK3) in Urine Identifies Patients with Short-Term Risk of eGFR Loss.Journal of the American Society of Nephrology : JASN · 2018Trial
- Evolving kidney disease phenotypes in type 2 diabetes: declining albuminuria and increasing isolated low eGFR.Clinical kidney journal · 2026Article
- Therapeutic Advances in Diabetic Kidney Disease: 30 Years of Evidence and the Rise of the "Fantastic Four" in Nephrology.Cardiorenal medicine · 2026Review
- Serum Uric Acid to Creatinine Ratio as a Predictor of Normoalbuminuric DKD in T2DM with Normal Renal Function.International journal of general medicine · 2026Article
- Association of normal range of urinary albumin-to-creatinine ratio with all-cause mortality among diabetic adults with preserved kidney function: National Health and Nutrition Examination Survey (NHANES) 2003-2018.Diabetes, obesity & metabolism · 2025Article
- Lipidomics reveals potential biomarkers and pathophysiological insights in the progression of diabetic kidney disease.Metabolism open · 2025Article
- Association of Sleep Duration With Serum Estradiol Concentrations Among American Men and Women: Evidence From NHANES 2013-2016.International journal of endocrinology · 2025Article
- Association of dietary inflammatory index and oxidative balance score with all-cause and cardiovascular mortality in US non-diabetic adults.Frontiers in nutrition · 2025Article
- Sex differences in the impact of controlling nutritional status score on diabetic retinopathy: findings of 2003-2018 National Health and Nutrition Examination Survey.Frontiers in nutrition · 2025Article
- The serum uric acid to creatinine ratio as a diagnostic biomarker for normoalbuminuric diabetic kidney disease.Frontiers in medicine · 2025Article
- The relationship between advanced glycation end products, metabolic metrics, HbAFrontiers in endocrinology · 2025Article
- Urinary non-albumin protein-creatinine ratio is an independent predictor of mortality in patients with type 2 diabetes: a retrospective cohort study.Scientific reports · 2024Article
- Conditional associations of sex steroid hormones with C-reactive protein levels in American children and adolescents: evidence from NHANES 2015-2016.Frontiers in endocrinology · 2024Article
- Associations between Waist Circumference and Sex Steroid Hormones in US Adult Men: Cross-Sectional Findings from the NHANES 2013-2016.International journal of endocrinology · 2024Article
- Circulating metabolites improve the prediction of renal impairment in patients with type 2 diabetes.BMJ open diabetes research & care · 2023Article
- Mitochondrial DNA Changes in Blood and Urine Display a Specific Signature in Relation to Inflammation in Normoalbuminuric Diabetic Kidney Disease in Type 2 Diabetes Mellitus Patients.International journal of molecular sciences · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
objectiveImproved blood pressure control and use of renin-angiotensin-aldosterone system blockers have altered the clinical presentation or phenotype of chronic kidney disease (CKD) in U.S. adults with diabetes. These changes may influence mortality. RESEARCH DESIGN AND
methodsData from the National Health and Nutrition Examination Surveys (NHANES) 1988-2006 were used to examine mortality trends in adults with diabetes, defined as physician diagnosis, fasting glucose ≥126 mg/dL, HbA
resultsFrom 1988 to 2006, adults with an eGFR <60 mL/min/1.73 m
conclusionsACR values are decreasing in U.S. adults with diabetes, but optimal management strategies are needed to reduce mortality in those with a low eGFR and an ACR <30 mg/g.
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Registered trials
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