ArticleClinical chemistry2018
Establishment of Community-Based Reference Intervals for Fructosamine, Glycated Albumin, and 1,5-Anhydroglucitol.
Article in Clinical chemistry, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.
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Who cites it
37 citing papers in PubMed, 1 synthesis or guideline pooled it, 80 citations in OpenAlex.
- Potential Markers of Dietary Glycemic Exposures for Sustained Dietary Interventions in Populations without Diabetes.Advances in nutrition (Bethesda, Md.) · 2020Pooled it
- Clinical Outcomes and Management in Late Diagnosed Siblings Affected With Attenuated GSD Ib.JIMD reports · 2026Article
- Glycated albumin and composite glycemic-lipid indices: complementary tools for type 2 diabetes diagnosis.Journal of biomedical research · 2025Article
- Article
- Reference Interval for Glycated Albumin, 1,5-AG/GA, and GA/HbA1c Ratios and Cut-Off Values for Type 1, Type 2, and Gestational Diabetes: A Cross-Sectional Study.Biomedicines · 2024Article
- Cutoff Values for Glycated Albumin, 1,5-Anhydroglucitol, and Fructosamine as Alternative Markers for Hyperglycemia.Journal of clinical laboratory analysis · 2024Article
- The clinical potential of 1,5-anhydroglucitol as biomarker in diabetes mellitus.Frontiers in endocrinology · 2024Review
- The progress of clinical research on the detection of 1,5-anhydroglucitol in diabetes and its complications.Frontiers in endocrinology · 2024Review
- Glycated Albumin Correlates With Time-in-Range Better Than HbA1c or Fructosamine.The Journal of clinical endocrinology and metabolism · 2023Article
- Glycated serum proteins and albumin but not glycated albumin show negative correlation with BMI in an overweight/obese, diabetic population from the United States.Clinical biochemistry · 2023Article
- Inverse Associations between Measures of Adiposity and Glycated Albumin in US Adults, NHANES 1999-2004.The journal of applied laboratory medicine · 2023Article
- Prepregnancy body mass index and glycated albumin in the third trimester may predict infant complications in gestational diabetes mellitus: a retrospective cohort study.Diabetology international · 2023Article
- Analytical performances of a glycated albumin assay that is traceable to standard reference materials and reference range determination.Journal of clinical laboratory analysis · 2022Article
- Associations of Glycated Albumin and HbA1c with Chronic Kidney Disease in US Adults.The journal of applied laboratory medicine · 2022Article
- Assessment of glycemia in chronic kidney disease.BMC medicine · 2022Review
- Glycated Albumin: Added Value or Redundancy in Diabetes Care?Clinical chemistry · 2022Article
- Glycated Albumin for the Diagnosis of Diabetes in US Adults.Clinical chemistry · 2022Article
- Maternal serum fructosamine levels and stillbirth: a case-control study of the Stillbirth Collaborative Research Network.BJOG : an international journal of obstetrics and gynaecology · 2022Article
- Recent Developments in Biomarkers for Diagnosis and Screening of Type 2 Diabetes Mellitus.Current diabetes reports · 2022Review
- Glycated albumin and HbA1c as markers of lower extremity disease inUS adults with and without diabetes.Diabetes research and clinical practice · 2022Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundThere is growing interest in fructosamine, glycated albumin, and 1,5-anhydroglucitol (1,5-AG) as alternative measures of hyperglycemia, particularly for use in settings where traditional measures (glucose and HbA1c) are problematic or where intermediate (2-4 weeks) glycemic control is of interest. However, reference intervals for these alternative biomarkers are not established.
methodsWe measured fructosamine, glycated albumin, and 1,5-AG in a community-based sample of US black and white adults who participated in the Atherosclerosis Risk in Communities (ARIC) Study. We calculated reference intervals, evaluated demographic differences, and derived cutoffs aligned with current diagnostic cutpoints for HbA1c and fasting glucose.
resultsIn a healthy reference population of 1799 individuals (mean age, 55 years; 51% women; 15% black), the 2.5 and 97.5 percentiles, respectively, were 194.8 and 258.0 μmol/L for fructosamine, 10.7% and 15.1% for glycated albumin, and 8.4 and 28.7 μg/mL for 1,5-AG. Distributions differed by race, sex, and body mass index. Equivalent concentrations of fructosamine and glycated albumin corresponding to an HbA1c of 6.5% (96.5 percentile) were 270.2 μmol/L and 15.6%, respectively. Equivalent concentrations of fructosamine and glycated albumin corresponding to a fasting glucose of 126 mg/dL (93.9 percentile) were 261.7 μmol/L and 15.0%, respectively.
conclusionsThe reference intervals for these biomarkers should inform their clinical use. Diagnostic cutpoint equivalents for fructosamine and glycated albumin could be useful to identify persons with hyperglycemia in settings where fasting glucose or HbA1c are not available or where the interpretation of these traditional measures is problematic.
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