Evidence map›Paper›PMID 29436246›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019

Oscillating-gradient diffusion magnetic resonance imaging detects acute subcellular structural changes in the mouse forebrain after neonatal hypoxia-ischemia.

Dan Wu, Lee J Martin, Frances J Northington, Jiangyang Zhang

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.6field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 25 citations in OpenAlex.

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  8. Feasibility of oscillating and pulsed gradient diffusion MRI to assess neonatal hypoxia-ischemia on clinical systems.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 2 countries.

Dan Wu1 Key Laboratory for Biomedical Engineering of Ministry of Education, College of Biomedical Engineering & Instrument Science, Zhejiang University, Hangzhou, China.
Lee J Martin3 Department of Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Frances J Northington5 Department of Pediatrics, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Jiangyang Zhang6 Department of Radiology, New York University School of Medicine, New York, NY, USA.
Johns Hopkins Medicine · USJohns Hopkins University · USNew York University · USZhejiang University · CN

Funding

Imaging Neonatal Hypoxic Ischemic InjuryR01HD074593 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FRANCES J NORTHINGTON, JIANGYANG ZHANG · 2013 to 2026
$6.8M
Quantitative Imaging of Mouse Brain DevelopmentR01NS102904 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ZHANG, JIANGYANG · 2018 to 2022
$3.1M
Mechanisms of Hypothermic Neuroprotection in NeonatesR01HD070996 · NICHD · JOHNS HOPKINS UNIVERSITY · PI NORTHINGTON, FRANCES J · 2012 to 2016
$1.7M
In-utero characterization of embryonic mouse brain development and injury with MRIR21NS098018 · NINDS · JOHNS HOPKINS UNIVERSITY · PI WU, DAN · 2016 to 2017
$461k
NICHD NIH HHS R01 HD070996NICHD NIH HHS R01 HD074593NINDS NIH HHS R01 NS102904NINDS NIH HHS R21 NS098018
6 · The paper itself

Abstract

The recently developed oscillating-gradient diffusion MRI (OG-dMRI) technique extends our ability to examine brain structures at different spatial scales. In this study, we investigated the sensitivity of OG-dMRI in detecting cellular and subcellular structural changes in a mouse model of neonatal hypoxia ischemia (HI). Neonatal mice received unilateral HI injury or sham injury at postnatal day 10, followed by in vivo T

Indexed as

Animals, NewbornAnimalsBrain EdemaCarotid ArteriesCerebral CortexDiffusion Magnetic Resonance ImagingDisease Models, AnimalHippocampusHypoxia-Ischemia, BrainLigationMiceMitochondriaNeurogliaNeuronsProsencephalonneonatal hypoxia-ischemiaOscillating-gradient diffusion magnetic resonance imagingpseudo-normalizationsubcellular structural change

Identifiers

PMID29436246
PMCPMC6668516
OpenAlexW2791211012

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.