Evidence map›Paper›PMID 29436245›Full record

ArticleThe Journal of international medical research2018

Vitamin A intake of Brazilian mothers and retinol concentrations in maternal blood, human milk, and the umbilical cord.

Thalia Manfrin Martins Deminice, Ivan Savioli Ferraz, Jacqueline Pontes Monteiro, Alceu Afonso Jordão, Lívia Maria Cordeiro Simões Ambrósio, Carlos Alberto Nogueira-de-Almeida

Open access · goldAbstract read
In one paragraph

Article in The Journal of international medical research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Vitamin A Requirements in Pregnancy and Lactation.Current developments in nutrition · 2020
    Review
  9. Review
  10. Observational
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Thalia Manfrin Martins Deminice1 Department of Puericulture and Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, Monte Alegre, Ribeirão Preto/SP, Brazil.
Ivan Savioli Ferraz1 Department of Puericulture and Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, Monte Alegre, Ribeirão Preto/SP, Brazil.ORCID http://orcid.org/0000-0003-3464-6523
Jacqueline Pontes Monteiro1 Department of Puericulture and Pediatrics, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, Monte Alegre, Ribeirão Preto/SP, Brazil.
Alceu Afonso Jordão2 Nutrition and Metabolism Division of the Department of Health Sciences, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, Monte Alegre, Ribeirão Preto/SP, Brazil.
Lívia Maria Cordeiro Simões Ambrósio3 Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Av. Bandeirantes, Monte Alegre, Ribeirão Preto/SP, Brazil.
Carlos Alberto Nogueira-de-Almeida4 Medical Department, Federal University of São Carlos - UFSCAR, São Carlos, Rua Eugenio Ferrante, Jd. Nova Alianca Sul, SP, Brazil.ORCID http://orcid.org/0000-0003-1272-4404
Universidade de São Paulo · BRUniversidade Federal de São Carlos · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives To analyse intake of vitamin A (VA) and retinol concentrations in maternal blood, breast milk (BM), and the umbilical cord (UC) of newborns, and to determine the associations among these variables. Methods We performed a cross-sectional, epidemiological study of 180 mother-newborn dyads. Maternal and UC blood samples and BM were collected. VA intake by the mother over 30 days was assessed using a questionnaire. Results Mean retinol concentrations in maternal serum, the UC, and BM were 0.65 ± 0.27, 0.36 ± 0.18, and 2.95 ± 2.70 µmol/L, respectively. Retinol concentrations <0.70 µmol/L were found in 57.2% of maternal blood samples and in 94.9% of UC samples. A total of 27.9% of BM samples showed retinol concentrations <1.05 µmol/L. Mean VA intake by the mothers was 1041.33 ± 1187.86 µg retinol activity equivalents/day and was inadequate (<550 µg retinol activity equivalents/day) in 44.7%. Conclusions High proportions of insufficient retinol concentrations were observed in the UC, maternal blood, and BM. A high percentage of pregnant women had inadequate VA intake. Mothers with insufficient serum retinol concentrations had newborns with lower retinol concentrations in the UC. Higher retinol concentrations were observed in maternal blood and the UC with a higher VA intake.

Indexed as

MothersAdultBrazilDemographyFemaleHospitals, MaternityHospitals, PublicHumansInfant, NewbornMilk, HumanUmbilical CordVitamin AVitamin Acolostrummaternal bloodnewbornRetinolumbilical cordvitamin A deficiency

Identifiers

PMID29436245
PMCPMC6091812
OpenAlexW2786091056

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.