Evidence map›Paper›PMID 29436184›Full record

ReviewYonsei medical journal2018

Systems Biology-Based Platforms to Accelerate Research of Emerging Infectious Diseases.

Soo Jin Oh, Young Ki Choi, Ok Sarah Shin

Open access · goldAbstract readReview
In one paragraph

Review in Yonsei medical journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Computational tools for modern vaccine development.Human vaccines & immunotherapeutics · 2020
    Review
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Soo Jin OhDepartment of Biomedical Sciences, College of Medicine, Korea University Guro Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0001-5423-0440
Young Ki ChoiCollege of Medicine and Medical Research Institute, Chungbuk National University, Cheongju, Korea.ORCID https://orcid.org/0000-0002-1894-9869
Ok Sarah ShinDepartment of Biomedical Sciences, College of Medicine, Korea University Guro Hospital, Seoul, Korea. oshin@korea.ac.kr.ORCID https://orcid.org/0000-0002-3977-2492
Korea University Medical Center · KRChungbuk National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Emerging infectious diseases (EIDs) pose a major threat to public health and security. Given the dynamic nature and significant impact of EIDs, the most effective way to prevent and protect against them is to develop vaccines in advance. Systems biology approaches provide an integrative way to understand the complex immune response to pathogens. They can lead to a greater understanding of EID pathogenesis and facilitate the evaluation of newly developed vaccine-induced immunity in a timely manner. In recent years, advances in high throughput technologies have enabled researchers to successfully apply systems biology methods to analyze immune responses to a variety of pathogens and vaccines. Despite recent advances, computational and biological challenges impede wider application of systems biology approaches. This review highlights recent advances in the fields of systems immunology and vaccinology, and presents ways that systems biology-based platforms can be applied to accelerate a deeper understanding of the molecular mechanisms of immunity against EIDs.

Indexed as

Communicable Diseases, EmergingImmunityHumansResearchSystems BiologyVaccinesVaccinesEmerging infectious diseasesimmunitysystems biologysystems vaccinologyvaccines

Identifiers

PMID29436184
PMCPMC5823818
OpenAlexW2786953468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.