Evidence map›Paper›PMID 29435993›Full record

ArticleThe Journal of physiology2018

Different role of TTX-sensitive voltage-gated sodium channel (Na

M Kollarik, H Sun, R A Herbstsomer, F Ru, M Kocmalova, S N Meeker, B J Undem

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 38 citations in OpenAlex.

  1. Trial
  2. Article
  3. The potential for NaThe Journal of physiology · 2023
    Article
  4. Role of NaThe Journal of physiology · 2023
    Article
  5. Review
  6. Role of NaBritish journal of pharmacology · 2022
    Article
  7. Contribution of tetrodotoxin-sensitive, voltage-gated sodium channels (NaAmerican journal of physiology. Regulatory, integrative and comparative physiology · 2021
    Article
  8. Article
  9. Antitussive effects of NaEuropean journal of pharmacology · 2021
    Article
  10. Article
  11. Review
  12. Stimulus intensity-dependent recruitment of NaAmerican journal of physiology. Gastrointestinal and liver physiology · 2020
    Article
  13. Review
  14. Review
  15. The voltage-gated sodium channel NaRespiratory physiology & neurobiology · 2019
    Article
  16. Targeting C-fibers for peripheral acting anti-tussive drugs.Pulmonary pharmacology & therapeutics · 2019
    Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

M KollarikDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-9659-5007
H SunDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
R A HerbstsomerDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0002-2303-0144
F RuDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
M KocmalovaDepartment of Pharmacology, Biomedical Center Martin, Jessenius Faculty of Medicine in Martin, Comenius University in Bratislava, Martin, Slovakia.ORCID 0000-0001-9510-7764
S N MeekerDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.
B J UndemDepartment of Medicine, The Johns Hopkins University School of Medicine, Baltimore, MD, USA.ORCID 0000-0001-5299-9029
Johns Hopkins University · USComenius University Bratislava · SK

Funding

Control of Airway Sensory Nerve Function by Voltage-Gated Sodium Channel SubtypesR01HL122228 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI UNDEM, BRADLEY JOEL · 2014 to 2020
$3.2M
Identification and Activation Mechanisms of Vagal and Spinal Nociceptors in Esophageal MucosaR01DK110366 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI TAYLOR-CLARK, THOMAS EDWARD, YU, SHAOYONG · 2017 to 2020
$1.4M
Ionic and Structural Mechanisms for Sensory Neuromodulation of the EsophagusU01DK116311 · NIDDK · UNIVERSITY OF SOUTH FLORIDA · PI TAYLOR-CLARK, THOMAS EDWARD · 2017 to 2019
$786k
NHLBI NIH HHS R01 HL122228NIDDK NIH HHS R01 DK110366NIDDK NIH HHS U01 DK116311
6 · The paper itself

Abstract

key pointsThe action potential initiation in the nerve terminals and its subsequent conduction along the axons of afferent nerves are not necessarily dependent on the same voltage-gated sodium channel (Na ABSTRACT: The action potential (AP) initiation in the nerve terminals and its subsequent AP conduction along the axons do not necessarily depend on the same subtypes of voltage-gated sodium channels (Na

Indexed as

Action PotentialsAnimalsGuinea PigsLungMaleNociceptorsTetrodotoxinTracheaVagus NerveVoltage-Gated Sodium Channel BlockersVoltage-Gated Sodium ChannelsTetrodotoxinVoltage-Gated Sodium Channel BlockersVoltage-Gated Sodium ChannelsAirwaysC fibreVagus nervevoltage-gated sodium channels

Identifiers

PMID29435993
PMCPMC5899984
OpenAlexW2799524133

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.