Evidence map›Paper›PMID 29435829›Full record

ReviewJournal of neurovirology2018

An SIV macaque model of SIV and HAND: the need for adjunctive therapies in HIV that target activated monocytes and macrophages.

Jaclyn Mallard, Kenneth Williams

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Journal of neurovirology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Review
  7. Dopamine, Immunity, and Disease.Pharmacological reviews · 2023
    Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Role of T Lymphocytes in HIV Neuropathogenesis.Current HIV/AIDS reports · 2019
    Review
  16. Review
  17. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Jaclyn MallardDepartment of Biology, Boston College, Chestnut Hill, MA, 02467, USA.
Kenneth WilliamsDepartment of Biology, Boston College, Chestnut Hill, MA, 02467, USA. Kenneth.williams.3@bc.edu.ORCID 0000-0002-6394-539X

Funding

NIH HHS RO1 NS04237
6 · The paper itself

Abstract

Non-human primate models of AIDS and neuroAIDS are critical to study HIV infection of the CNS, neuropathology, and immune activation and macrophage accumulation that occurs in HAND. SIV, similar to HIV, infects CD4

Indexed as

Disease Models, AnimalAnimalsAntiretroviral Therapy, Highly ActiveAntiviral AgentsCentral Nervous SystemCognitive DysfunctionDrug Therapy, CombinationHumansMacaca mulattaMacrophagesMinocyclineMitoguazoneNatalizumabSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency VirusT-LymphocytesAntiviral AgentsMinocyclineMitoguazoneNatalizumabHANDHIVMacrophagesMonocyteSIV

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.