Evidence map›Paper›PMID 29435761›Full record

ArticleHistochemistry and cell biology2018

Fibroblasts potentiate melanoma cells in vitro invasiveness induced by UV-irradiated keratinocytes.

Njainday Pulo Jobe, Veronika Živicová, Alžběta Mifková, Daniel Rösel, Barbora Dvořánková, Ondřej Kodet, Hynek Strnad, Michal Kolář, Aleksi Šedo, Karel Smetana and 3 more

Abstract read
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In one paragraph

Article in Histochemistry and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Article
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  4. Review
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  9. Article
  10. The Abscopal Effect in the Era of Checkpoint Inhibitors.International journal of molecular sciences · 2021
    Review
  11. Article
  12. Effect of Different Wavelengths of Laser Irradiation on the Skin Cells.International journal of molecular sciences · 2021
    Review
  13. Review
  14. Article
  15. Interleukin-6: Molecule in the Intersection of Cancer, Ageing and COVID-19.International journal of molecular sciences · 2020
    Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Njainday Pulo JobeDepartment of Cell Biology, Faculty of Sciences, Charles University in Prague, Viničná 7, 120 00, Prague 2, Czech Republic.
Veronika ŽivicováInstitute of Anatomy, 1st Faculty of Medicine, Charles University, U Nemocnice 3, Prague 2, Czech Republic.
Alžběta MifkováInstitute of Anatomy, 1st Faculty of Medicine, Charles University, U Nemocnice 3, Prague 2, Czech Republic.
Daniel RöselDepartment of Cell Biology, Faculty of Sciences, Charles University in Prague, Viničná 7, 120 00, Prague 2, Czech Republic.
Barbora DvořánkováBiotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec (BIOCEV), Průmyslová 595, Vestec u Prahy, Prague, Czech Republic.
Ondřej KodetBiotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec (BIOCEV), Průmyslová 595, Vestec u Prahy, Prague, Czech Republic.
Hynek StrnadInstitute of Molecular Genetics, Academy of Sciences of the Czech Republic vvi, Vídeňská 1083, Prague 4, Czech Republic.
Michal KolářInstitute of Molecular Genetics, Academy of Sciences of the Czech Republic vvi, Vídeňská 1083, Prague 4, Czech Republic.
Aleksi ŠedoInstitute of Biochemistry and Experimental Oncology, 1st Faculty of Medicine, Charles University, U Nemocnice 5, Prague 2, Czech Republic.
Karel SmetanaBiotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec (BIOCEV), Průmyslová 595, Vestec u Prahy, Prague, Czech Republic.
Karolina StrnadováBiotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec (BIOCEV), Průmyslová 595, Vestec u Prahy, Prague, Czech Republic.
Jan BrábekDepartment of Cell Biology, Faculty of Sciences, Charles University in Prague, Viničná 7, 120 00, Prague 2, Czech Republic.
Lukáš LacinaBiotechnology and Biomedicine Center of the Academy of Sciences and Charles University in Vestec (BIOCEV), Průmyslová 595, Vestec u Prahy, Prague, Czech Republic. lukas.lacina@lf1.cuni.cz.ORCID http://orcid.org/0000-0002-1750-9933

Funding

Grantová Agentura České Republiky No. 16-05534SMinisterstvo Školství, Mládeže a Tělovýchovy CZ.1.05/1.1.00/02.0109Ministerstvo Školství, Mládeže a Tělovýchovy Project BIOCEV-FAR reg. No. LQ1604Ministerstvo Zdravotnictví Ceské Republiky 16-29032ARDIOP CZ.1.05/2.1.00/19.0400Univerzita Karlova v Praze Progress-28Univerzita Karlova v Praze UNCE 23014
6 · The paper itself

Abstract

Melanoma represents a malignant disease with steadily increasing incidence. UV-irradiation is a recognized key factor in melanoma initiation. Therefore, the efficient prevention of UV tissue damage bears a critical potential for melanoma prevention. In this study, we tested the effect of UV irradiation of normal keratinocytes and their consequent interaction with normal and cancer-associated fibroblasts isolated from melanoma, respectively. Using this model of UV influenced microenvironment, we measured melanoma cell migration in 3-D collagen gels. These interactions were studied using DNA microarray technology, immunofluorescence staining, single cell electrophoresis assay, viability (dead/life) cell detection methods, and migration analysis. We observed that three 10 mJ/cm

Indexed as

Neoplasm InvasivenessUltraviolet RaysCells, CulturedCoculture TechniquesFibroblastsHumansImmunohistochemistryKeratinocytesMelanomaCancer-associated fibroblastsCancer microenvironmentChemokineCytokineKeratinocytesMelanoma

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.