ArticleEJNMMI research2018
A new SPECT/CT reconstruction algorithm: reliability and accuracy in clinical routine for non-oncologic bone diseases.
Article in EJNMMI research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Super-Resolution Reconstruction and Detector Geometric Error Correction for Parallel-Beam Low-Resolution Multi-Detector SPECT: A Proof of Concept.Tomography (Ann Arbor, Mich.) · 2026Article
- The value ofQuantitative imaging in medicine and surgery · 2025Article
- A review of state-of-the-art resolution improvement techniques in SPECT imaging.EJNMMI physics · 2025Review
- Single photon emission computed tomography/computed tomography imaging of gouty arthritis: A new voice.Journal of translational internal medicine · 2024Article
- Detectability of cold tumors by xSPECT bone technology compared with hot tumors: a supine phantom study.Physical and engineering sciences in medicine · 2024Article
- Cardiac DPD-uptake time dependency in ATTR patients verified by quantitative SPECT/CT and semiquantitative planar parameters.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Article
- Monitoring tafamidis treatment with quantitative SPECT/CT in transthyretin amyloid cardiomyopathy.European heart journal. Cardiovascular Imaging · 2023Article
- Theranostic SPECT reconstruction for improved resolution: application to radionuclide therapy dosimetry.EJNMMI physics · 2021Article
- Bone Scintigraphy of Vertebral Fractures With a Whole-Body CZT Camera in a PET-Like Utilization.Frontiers in nuclear medicine · 2021Article
- In Vivo Quantification of Myocardial Amyloid Deposits in Patients with Suspected Transthyretin-Related Amyloidosis (ATTR).Journal of clinical medicine · 2020Article
- QuantitativeJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2020Article
- Phantom and clinical evaluation of bone SPECT/CT image reconstruction with xSPECT algorithm.EJNMMI research · 2020Article
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundxSPECT Bone® (xB) is a new reconstruction algorithm developed by Siemens® in bone hybrid imaging (SPECT/CT). A CT-based tissue segmentation is incorporated into SPECT reconstruction to provide SPECT images with bone anatomy appearance. The objectives of this study were to assess xB/CT reconstruction diagnostic reliability and accuracy in comparison with Flash 3D® (F3D)/CT in clinical routine. Two hundred thirteen consecutive patients referred to the Brest Nuclear Medicine Department for non-oncological bone diseases were evaluated retrospectively. Two hundred seven SPECT/CT were included. All SPECT/CT were independently interpreted by two nuclear medicine physicians (a junior and a senior expert) with xB/CT then with F3D/CT three months later. Inter-observer agreement (IOA) and diagnostic confidence were determined using McNemar test, and unweighted Kappa coefficient. The study objectives were then re-assessed for validation through > 18 months of clinical and paraclinical follow-up.
resultsNo statistically significant differences between IOA
conclusionsxB reconstruction algorithm was found reliable, providing high interobserver agreement and similar diagnostic confidence to F3D reconstruction in clinical routine.
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