Evidence map›Paper›PMID 29435486›Full record

ArticleeNeuro

Transient Receptor Potential Channels TRPM4 and TRPC3 Critically Contribute to Respiratory Motor Pattern Formation but not Rhythmogenesis in Rodent Brainstem Circuits.

Hidehiko Koizumi, Tibin T John, Justine X Chia, Mohammad F Tariq, Ryan S Phillips, Bryan Mosher, Yonghua Chen, Ryan Thompson, Ruli Zhang, Naohiro Koshiya and 1 more

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Review
  3. Interdependence of cellular and network properties in respiratory rhythm generation.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  4. Article
  5. Article
  6. Role of NaCell reports · 2023
    Article
  7. Article
  8. Inspiratory rhythm generation is stabilized byJournal of neurophysiology · 2022
    Article
  9. Review
  10. Dynamics of ramping bursts in a respiratory neuron model.Journal of computational neuroscience · 2022
    Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Hidehiko KoizumiCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-7747-3434
Tibin T JohnCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-6825-7166
Justine X ChiaCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-2530-767X
Mohammad F TariqCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Ryan S PhillipsCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Bryan MosherCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Yonghua ChenCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-9017-827X
Ryan ThompsonCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Ruli ZhangCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.
Naohiro KoshiyaCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-2952-8779
Jeffrey C SmithCellular and Systems Neurobiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892.ORCID 0000-0002-7676-4643
National Institutes of Health · US

Funding

UCD Mutant Mouse Regional Resource CenterU42OD012210 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI KC KENT LLOYD · 2012 to 2026
$29.2M
Neural Mechanisms Controlling Breathing In MammalsZIANS002899 · NINDS · NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE · PI SMITH, JEFFREY C · 2009 to 2023
$21.1M
NIH HHS U42 OD012210
6 · The paper itself

Abstract

Transient receptor potential channel, TRPM4, the putative molecular substrate for Ca

Indexed as

RespirationAnimalsBrain StemCentral Pattern GeneratorsGlutamic AcidGlycineMice, Inbred C57BLMice, TransgenicNeural PathwaysNeuronsPeriodicityRats, Sprague-DawleyRNA, MessengerTissue Culture TechniquesTRPC Cation ChannelsTRPM Cation ChannelsGlutamic AcidGlycineRNA, MessengerTRPC3 cation channelTRPC Cation ChannelsTRPM4 protein, mouseTRPM4 protein, ratTRPM Cation ChannelsBreathingdynamic calcium imagingICANpre-Bötzinger complex

Identifiers

PMID29435486
PMCPMC5806591
OpenAlexW2788533018

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.