ReviewTemperature (Austin, Tex.)2017
Pathophysiology of heatstroke in dogs - revisited.
Review in Temperature (Austin, Tex.), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
36 citing papers in PubMed, 61 citations in OpenAlex.
- Successful Intensive Management and Serial Clinical Progression of Severe Non-Exertional Heatstroke in a Cat Following Clothes Dryer Entrapment.Veterinary sciences · 2026Article
- Ultrasonographic and Thermographic Evaluation in Brachycephalic Dogs Before and After Physical Exercise in the Brazilian Northeast Semi-Arid Region.Veterinary sciences · 2026Article
- RECOVER Guidelines: First Aid in Dogs and Cats. Evidence and Knowledge Gap Analysis With Treatment Recommendations.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026Article
- RECOVER Guidelines: First Aid for Dogs and Cats. Clinical Guidelines.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001) · 2026Article
- Cool and safe walks: heat stress threshold for domestic dogs living in hot and sunny regions.International journal of biometeorology · 2026Article
- Reference Interval Determination for Digital Rectal Temperature in Healthy Ferrets (Animals : an open access journal from MDPI · 2026Article
- Evaluation and validation of a revised VetCompass clinical grading tool for heat-related illness in dogs.Scientific reports · 2026Article
- Assessing the welfare of dogs surgically sterilized during single day free community pet clinics in Kampala Metropolitan area, Central Uganda.Animal welfare (South Mimms, England) · 2026Article
- Feeling the heat: associations among daily ambient temperatures, extreme heat days and risk mortality in Australian dogs from New South Wales (1997-2017).Australian veterinary journal · 2025Article
- Detection Dogs Working in Hot Climates: The Influence on Thermoregulation and Fecal Consistency.Animals : an open access journal from MDPI · 2024Article
- Article
- Infrared Thermography in Assessment of Facial Temperature of Racing Sighthound-Type Dogs in Different Environmental Conditions.Animals : an open access journal from MDPI · 2024Article
- A Randomized Cross-Over Study Comparing Cooling Methods for Exercise-Induced Hyperthermia in Working Dogs in Training.Animals : an open access journal from MDPI · 2023Article
- Article
- Scientific and technical assistance on welfare aspects related to housing and health of cats and dogs in commercial breeding establishments.EFSA journal. European Food Safety Authority · 2023Article
- Cooling Methods Used to Manage Heat-Related Illness in Dogs Presented to Primary Care Veterinary Practices during 2016-2018 in the UK.Veterinary sciences · 2023Article
- The effect of the surgical treatment of brachycephalic obstructive airway syndrome on the thermoregulatory response to exercise in French bulldogs: a pilot study.Frontiers in veterinary science · 2023Article
- The health of working dogs in conservation in Africa.Frontiers in veterinary science · 2023Article
- The Rise of Heatstroke as a Method of Depopulating Pigs and Poultry: Implications for the US Veterinary Profession.Animals : an open access journal from MDPI · 2022Article
- Encephalic meningioangiomatosis in a cat.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heatstroke results from a failure to dissipate accumulated heat during exposure to hot environments, or during strenuous physical exercise under heat stress. It is characterized by core body temperatures > 41°C, with central nervous system dysfunction. Functional morphology and thermoregulatory effectors differences between dogs and humans may require special heatstroke protective adaptations in dogs, however, the risk factors for developing heatstroke are similar in both. In dogs, these include hot, especially highly humid environments, excessive physical activity, obesity, large (>15 kg) body weight, being of certain breed (e.g., Labrador retrievers and brachycephalic breeds), upper airway obstruction and prolonged seizures. Lack of acclimation to heat and physical fitness decreases the survival of heat stroked dogs. At the systemic level, blood pooling within the large internal organs (e.g., spleen, liver) is a major contributor to the development of shock and consequent intestinal ischemia, hypoxia and endothelial hyperpermeability, commonly occurring in heatstroke patients. Evoked serious complications include rhabdomyolysis, acute kidney injury, acute respiratory distress syndrome and ultimately, sepsis and disseminated intravascular coagulation. The most common clinical signs in dogs include acute collapse, tachypnea, spontaneous bleeding, shock signs and mental abnormalities, including depression, disorientation or delirium, seizures, stupor and coma. In such dogs, presence of peripheral blood nucleated red blood cells uniquely occurs, and is a highly sensitive diagnostic and prognostic biomarker. Despite early, appropriate body cooling, and intensive supportive treatment, with no available specific treatment to ameliorate the severe inflammatory and hemostatic derangements, the mortality rate is around 50%, similar to that of human heatstroke victims. This review discusses the pathophysiology of canine heatstroke from a veterinarian's point of view, integrating new and old studies and knowledge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.