Evidence map›Paper›PMID 29435349›Full record

ArticleBMJ open diabetes research & care2017

All-cause mortality in adults with and without type 2 diabetes: findings from the national health monitoring in Germany.

Susanne Röckl, Ralph Brinks, Jens Baumert, Rebecca Paprott, Yong Du, Christin Heidemann, Christa Scheidt-Nave

Erratum issuedAbstract read
In one paragraph

Article in BMJ open diabetes research & care, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Susanne RöcklDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.ORCID 0000-0001-5496-4014
Ralph BrinksInstitute of Biometry and Epidemiology, German Diabetes Center, Düsseldorf, Germany.
Jens BaumertDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Rebecca PaprottDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Yong DuDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Christin HeidemannDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.
Christa Scheidt-NaveDepartment of Epidemiology and Health Monitoring, Robert Koch Institute, Berlin, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo estimate age-specific and sex-specific all-cause mortality among adults with and without type 2 diabetes (T2D) in Germany. RESEARCH DESIGN AND

methodsThe German National Health Interview and Examination Survey 1998 (GNHIES98) included a mortality follow-up (median follow-up time 12.0 years) of its nationwide sample representative of the population aged 18-79 years. After exclusion of participants with type 1 diabetes, age- and sex-stratified mortality rates (MR) were calculated for 330 GNHIES98 participants with diagnosed T2D (self-reported diagnosis or antidiabetic medication), 245 with undiagnosed T2D (no diagnosed T2D, glycated hemoglobin A1c ≥6.5% (≥48 mmol/mol)), and 5975 without T2D. Mortality rate ratios (MRR) comparing MR of persons with and without T2D were estimated. Age-/sex-standardized MR and MRR were calculated including persons aged 45 years or older. MRR were used to estimate the number of years of life lost (YLL) due to diagnosed diabetes in 2010.

resultsOver 75 994 person-years, 73 persons with undiagnosed T2D, 103 with diagnosed T2D, and 425 persons without T2D died. MRR were significantly higher in younger age groups, except for analyses limited to women or diagnosed T2D. Age- and sex-standardized MRR (95% CI) among persons aged 45 years or older were 1.96 (1.41 to 2.71) for undiagnosed, 1.68 (1.26 to 2.23) for diagnosed, and 1.82 (1.45 to 2.28) for total (undiagnosed or diagnosed) T2D. Sex-stratified analysis revealed similar age-standardized MRR for undiagnosed (1.56 (0.79 to 3.06)) and diagnosed T2D (1.56 (1.03 to 2.37)) among women, and a higher age-standardized MRR for undiagnosed (2.06 (1.43 to 2.97)) than diagnosed T2D (1.70 (1.10 to 2.63)) among men. YLL due to diagnosed diabetes in Germany in 2010 were 164 600 (35 000 to 279 300) among women and 169 900 (28 300 to 328 300) among men.

conclusionsIn Germany, age- and sex-standardized all-cause mortality is almost twice as high for adults with T2D as for adults without T2D. The T2D-associated excess risk of mortality appears to be most pronounced in younger adults and among men unaware of their T2D.

Indexed as

mortalitynational health surveyspublic health/surveillancetype 2 diabetes

Identifiers

PMID29435349
PMCPMC5759714

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.